Ticagrelor Impurity 43 CAS 145783-13-7
| CAS No. | 145783-13-7 |
| Molecular Formula | C7H9N3O4S |
| Molecular Weight | 231.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Ticagrelor Impurity 43 (CAS 145783-13-7) is a certified pharmaceutical impurity reference standard with the molecular formula C7H9N3O4S and a molecular weight of 231.23 g/mol.
Structurally, Ticagrelor Impurity 43 (C7H9N3O4S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 231.23 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H9N3O4S |
| Molecular Weight | 231.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Ticagrelor Standards
- Ticagrelor Impurity 158 (CAS 1402150-27-9)
- Ticagrelor Impurity 62 (CAS CATO-C4X-109362)
- Ticagrelor Impurity 61 (CAS CATO-C4X-109361)
- Ticagrelor Impurity 39 (CAS 1431867-40-1)
- Ticagrelor Impurity 100 (CAS 39856-08-1)
- Ticagrelor Impurity 88 (CAS 1006376-61-9)
- Ticagrelor Impurity 44 (CAS 145783-15-9)
- Ticagrelor impurity 95 (CAS CATO-C4X-109395)
Recommended Standards
- 4-Nitrobenzyl Mesylate (CAS 39628-94-9)
- Sulpiride EP Impurity D (CAS 22117-85-7)
- Ethyl 4-nitrobenzenesulfonate (CAS 15481-55-7)
- Bumetanide Impurity 41 (CAS 20532-06-3)
- Gabapentin EP Impurity A (CAS 64744-50-9)
- Febuxostat Impurity 111 (CAS CATO-C4X-1162111)
- Bisoprolol Impurity 97 (CAS CATO-C4X-124797)
- N1-cyclohexyl-N2-(3,4-dichlorophenyl)oxalamide (CAS 329078-61-7)
- 2-(Azepan-1-yl)pyrimidine-5-carbaldehyde (CAS 1339348-75-2)
- Formoterol (Mixture of Diastereomers) (CAS 128954-45-0)
- (H-Cys-Phe-OH)2 (Disulfide bond) (CAS 62130-80-7)
- Diethyl 2-Chlorobenzylphosphonate (CAS 29074-98-4)
- 7-Bromo-3-methylimidazo[1,5-α]pyridine (CAS 1379355-19-7)
- Palmitoyl Tetrapeptide-7 (CAS 221227-05-0)
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