Zidovudine EP Impurity G CAS 148665-49-0
| CAS No. | 148665-49-0 |
| Molecular Formula | C20H25N7O8 |
| Molecular Weight | 491.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C20H25N7O8, Zidovudine EP Impurity G contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 491.45 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Zidovudine EP Impurity G (CAS 148665-49-0), a pharmacopoeial impurity reference standard (molecular formula C20H25N7O8, MW 491.45 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H25N7O8 |
| Molecular Weight | 491.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Nitrogen Atoms | 7 |
Related Zidovudine Standards
- Zidovudine EP Impurity J (CAS 29706-84-1)
- Zidovudine-5-Glucuronide (CAS 117675-21-5)
- Zidovudine Impurity 20 (CAS 244226-72-0)
- Zidovudine RC 2 (CAS 42214-24-4)
- Zidovudine Monophosphate (CAS 29706-85-2)
- Zidovudine Impurity N1 (CAS 365-07-1)
- Zidovudine EP Impurity K (CAS 596-31-6)
- Zidovudine-d4 (CAS CATO-C4X-178320)
Recommended Standards
- Dapagliflozin Impurity 24 (CAS 2176485-21-3)
- 8-(Difluoromethoxy)-1-ethyl-6-fluoro-7-(4-(2-methoxyphenyl)piperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 153468-00-9)
- 4-7-8-9-Tetra-O-acetyl-N-acetyl-D-neuraminic acid methyl ester (CAS 84380-10-9)
- (9S)-N-[3-(1,3-Oxazol-5-yl)phenyl]-5-[3-(trifluoromethyl)phenyl]-1,6,8-triazatricyclo[7.2.1.0,2,7]dodeca-2,4,6-triene-8-carboxamide (CAS 1638597-29-1)
- Vildagliptin Impurity 63 (CAS 62937-45-5)
- Anagrelide Impurity 37 (CAS CATO-C4X-224037)
- Iopromide EP Impurity F (Mixture of Diastereomers) (CAS 154361-54-3)
- (2S,3R)-3-Benzamido-2-hydroxy-3-phenylpropanoic acid (CAS 54323-80-7)
- Ethyl 5-(4-bromophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 313249-39-7)
- 5-Phenyl-1,3,4-thiadiazol-2-amine sulfate (CAS 340169-03-1)
- 2-(3-Fluorophenyl)pyrrolidine hydrochloride (CAS 1193390-31-6)
- 1-Benzyl-4-chloro-1H-pyrrolo[3,2-c]pyridine (CAS 35636-10-3)
- 2-(4-Bromo-6-chloropyridin-2-yl)acetonitrile (CAS 1805410-03-0)
- Fibrinogen Related Peptide (CAS 80755-86-8)
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