Etoposide EP Impurity R CAS 149839-65-6
| CAS No. | 149839-65-6 |
| Molecular Formula | C50H50O20 |
| Molecular Weight | 970.92 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Etoposide EP Impurity R (CAS 149839-65-6), a pharmacopoeial impurity reference standard (molecular formula C50H50O20, MW 970.92 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C50H50O20, Etoposide EP Impurity R contains a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 970.92 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C50H50O20 |
| Molecular Weight | 970.92 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 26.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
Related Etoposide Standards
- Etoposide EP Impurity N (CAS CATO-C4X-202414)
- Etoposide Impurity 28 (CAS CATO-C4X-202428)
- Etoposide Impurity 33 (CAS CATO-C4X-202433)
- Etoposide Impurity 37 (CAS CATO-C4X-202437)
- Etoposide impurity 20 (CAS CATO-C4X-202420)
- Etoposide Impurity 32 (CAS CATO-C4X-202432)
- Etoposide EP Impurity O (CAS 260974-95-6)
- Etoposide Impurity 39 (CAS CATO-C4X-202439)
Recommended Standards
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com