Cyanocobalamin EP Impurity G（50-methylcyanocobalamin） CAS 15130-04-8
| CAS No. | 15130-04-8 |
| Molecular Formula | C64H90CoN14O14P |
| Molecular Weight | 1369.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Cyanocobalamin EP Impurity G（50-methylcyanocobalamin） (C64H90CoN14O14P) contains a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 27.0, corresponding to approximately 27 ring(s) or double-bond equivalent(s). With a molecular weight of 1369.40 g/mol, it falls into the high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Cyanocobalamin EP Impurity G（50-methylcyanocobalamin） (CAS 15130-04-8), a pharmacopoeial impurity reference standard (molecular formula C64H90CoN14O14P, MW 1369.40 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C64H90CoN14O14P |
| Molecular Weight | 1369.40 g/mol |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 27.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 14 |
Related Cyanocobalamin Standards
- Cyanocobalamin Impurity 27 (CAS CATO-C4X-187427)
- Cyanocobalamin Impurity 24 (CAS CATO-C4X-187424)
- Cyanocobalamin Impurity 25 (CAS CATO-C4X-187425)
- Cyanocobalamin Impurity 26 (CAS CATO-C4X-187426)
- Cyanocobalamin EP Impurity B (CAS 26264-28-8)
- Cyanocobalamin /Vitamin B12 Impurity 22 (CAS 38437-93-3)
- Cyanocobalamin /Vitamin B12 Impurity 23 (CAS 38218-55-2)
- Cyanocobalamin EP Impurity D(Cyanocobalamin-b-monocarboxylic acid; 32-Carboxycyanocobalamin) (CAS 38218-77-8)
Recommended Standards
- O-(N-Fmoc-2-aminoethyl)-O-(2-carboxyethyl)undecaethyleneglycol (CAS 850312-72-0)
- 34-Methylcyanocobalamin(Cyanocobalamin EP Impurity C） (CAS 38218-51-8)
- Fmoc-N-PEG24-acid (CAS 2170484-59-8)
- Corazonin (CAS 122929-08-2)
- Citalopram Impurity 75 (CAS CATO-C4X-110975)
- Riboflavin Impurity 14 (CAS 21079-31-2)
- Olmesartan Impurity 41 (CAS 1443544-27-1)
- N-Allyl-2,6-dimethoxy-5-(methylthio)pyrimidin-4-amine (CAS 89587-77-9)
- (R)-1-(3-chloro-4-(trifluoromethoxy)phenyl)propan-1-amine (CAS 1213577-87-7)
- N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-2-methoxybenzamide (CAS 298207-74-6)
- 1-(1-Amino-2-methylpropan-2-yl)-3-methylcyclohexan-1-ol (CAS 1499417-85-4)
- Ethyl 4-hydroxy-6-methylpyrazolo[1,5-a]pyrazine-2-carboxylate, 97% (CAS 1443978-76-4)
- (2-Phenylbenzo[d]oxazol-5-yl)methanamine (CAS 864264-01-7)
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