Triamcinolone Acetonide EP Impurity E CAS 1524-86-3
| CAS No. | 1524-86-3 |
| Molecular Formula | C24H33FO6 |
| Molecular Weight | 436.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Triamcinolone Acetonide EP Impurity E under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Triamcinolone Acetonide EP Impurity E (CAS 1524-86-3), a pharmacopoeial impurity reference standard (molecular formula C24H33FO6, MW 436.51 g/mol) used for the identification and quantification of trace impurities in APIs.
Triamcinolone Acetonide EP Impurity E (C24H33FO6) contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C24H33FO6 |
| Molecular Weight | 436.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Triamcinolone Standards
- Triamcinolone EP Impurity B (CAS 3859-65-2)
- Triamcinolone Acetonide (CAS 76-25-5)
- Triamcinolone Acetonide-d6 (CAS 352431-33-5)
- Triamcinolone Acetonide Impurity N2 (CAS 1893-84-1)
- Triamcinolone Acetonide EP Impurity B (CAS 1260149-96-9)
- Triamcinolone Acetonide Impurity 44 (CAS CATO-C4X-132644)
- Triamcinolone Acetonide Impurity 38 (CAS CATO-C4X-132638)
- Triamcinolone Acetonide Impurity 49 (CAS 7704-77-0)
Recommended Standards
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- Ruxolitinib Impurity 25 (CAS CATO-C4X-205825)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com