Triamcinolone Acetonide Impurity N2 CAS 1893-84-1
| CAS No. | 1893-84-1 |
| Molecular Formula | C24H29FO6 |
| Molecular Weight | 432.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Triamcinolone Acetonide Impurity N2 (CAS 1893-84-1, C24H29FO6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C24H29FO6, Triamcinolone Acetonide Impurity N2 contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 432.48 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H29FO6 |
| Molecular Weight | 432.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Triamcinolone Standards
- Triamcinolone Acetonide EP Impurity B (CAS 1260149-96-9)
- Triamcinolone Acetonide (CAS 76-25-5)
- Triamcinolone EP Impurity B (CAS 3859-65-2)
- Triamcinolone Acetonide EP Impurity E (CAS 1524-86-3)
- Triamcinolone Acetonide-d6 (CAS 352431-33-5)
- Triamcinolone Impurity 10 (CAS 3800-28-0)
- Triamcinolone Acetonide Impurity 44 (CAS CATO-C4X-132644)
- Triamcinolone Acetonide Impurity 38 (CAS CATO-C4X-132638)
Recommended Standards
- Fluprednidene Acetate (CAS 1255-35-2)
- 1-(Furan-2-ylmethyl)-2-imino-10-methyl-3-(4-methylpiperazine-1-carbonyl)-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-5(2H)-one (CAS 510760-93-7)
- 21-Dehydro Flunisolide (CAS 1188271-69-3)
- 2-(3,4-Difluorophenyl)-4-(3-hydroxy-3-methylbutoxy)-5-(4-(methylthio)phenyl)pyridazin-3(2H)-one (CAS 266320-87-0)
- Tipiracil Impurity 6 (CAS 7544-75-4)
- Vildagliptin Impurity 9 (CAS CATO-C4X-11009)
- Tolvaptan Impurity 1 (CAS 247237-38-3)
- Naphthalene-1-diazonium tetrafluoroborate (CAS 28912-93-8)
- N-[4-[(Trifluoroacetyl)amino]benzoyl-d4]-L-glutamic Acid Dimethyl Ester (CAS 461426-33-5)
- Propylurea (CAS 627-06-5)
- 2-Amino-1-(1-methyl-1h-imidazol-2-yl)ethan-1-ol dihydrochloride (CAS 1197228-24-2)
- 3-[(dimethylamino)methyl]-1H-indole-6-carboxylic acid hydrochloride (CAS 1803580-99-5)
- 4-Bromo-3-methylbenzamidine hydrochloride (CAS 1187927-47-4)
- Des-Ser32-Tirzepatide (CAS CATO-CPTD788942)
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