Niraparib Impurity 35 CAS 1524736-92-2
| CAS No. | 1524736-92-2 |
| Molecular Formula | C16H23NO3 |
| Molecular Weight | 277.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Niraparib Impurity 35 (CAS 1524736-92-2, C16H23NO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Niraparib Impurity 35 (C16H23NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Niraparib Impurity 35 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H23NO3 |
| Molecular Weight | 277.36 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Nitrogen Atoms | 1 |
Related Niraparib Standards
- Niraparib Impurity 21 (CAS 1263284-59-8)
- Niraparib Impurity 3 (CAS 1171197-20-8)
- Niraparib Impurity 61 (CAS 3112957-16-8)
- Niraparib Impurity 64 (CAS 2820493-80-7)
- Niraparib Impurity 65 (CAS CATO-C4X-232965)
- Niraparib Impurity 60 (CAS CATO-C4X-232960)
- Niraparib Impurity 49 (CAS 1267209-15-3)
- Niraparib Impurity 48 (CAS 1823263-50-8)
Recommended Standards
- Tolperisone impurity 12 (CAS 59303-41-2)
- ZHC-116 Impurity 7 (CAS CATO-C4X-23887)
- Erdosteine Impurity 7 (CAS 84611-37-0)
- N-Acetylprocainamide (CAS 32795-44-1)
- Apalutamide Impurity 5 (CAS CATO-C4X-27495)
- Selexipag Impurity 1 (CAS CATO-C4X-19611)
- Isavuconazole Impurity 15 (CAS CATO-C4X-123615)
- 2-((5-Chloro-2-((4-morpholinophenyl)amino)pyrimidin-4-yl)amino)-N-methylbenzamide (CAS 1042432-58-5)
- 2-Bromo-3-chloro-1,8-naphthyridine (CAS 52626-32-1)
- Z-Ile-OH · DCHA (CAS 26699-00-3)
- [(1-Quinazolin-4-ylpiperidin-4-yl)methyl]amine (CAS 170353-27-2)
- (2S,3R)-2-((S)-2-(2,3-Dihydroxybenzamido)-5-guanidinopentanamido)-3-hydroxybutanoic acid (CAS 143651-45-0)
- 5-Hydroxy-1-(2-isopropylphenyl)pyrrolidine-3-carboxylic acid (CAS 1255147-59-1)
- (D-Ala2)-Gastric Inhibitory Polypeptide (human) trifluoroacetate salt (CAS 444073-04-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com