Niraparib Impurity 64 CAS 2820493-80-7
| CAS No. | 2820493-80-7 |
| Molecular Formula | C16H22N2O2 |
| Molecular Weight | 274.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Niraparib Impurity 64 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Niraparib Impurity 64 (CAS 2820493-80-7), a pharmacopoeial impurity reference standard (molecular formula C16H22N2O2, MW 274.36 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Niraparib Impurity 64 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 274.36 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C16H22N2O2 |
| Molecular Weight | 274.36 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Nitrogen Atoms | 2 |
Related Niraparib Standards
- Niraparib Impurity 61 (CAS 3112957-16-8)
- Niraparib Impurity 65 (CAS CATO-C4X-232965)
- Niraparib Impurity 21 (CAS 1263284-59-8)
- Niraparib Impurity 3 (CAS 1171197-20-8)
- Niraparib Impurity 60 (CAS CATO-C4X-232960)
- Niraparib Impurity 49 (CAS 1267209-15-3)
- Niraparib Impurity 35 (CAS 1524736-92-2)
- Niraparib Impurity 48 (CAS 1823263-50-8)
Recommended Standards
- Emedastine Impurity 46 (CAS CATO-C4X-226746)
- Sulfamethizole-d4 (CAS CATO-CCAD301426)
- Emedastine EP Impurity C (CAS 122423-32-9)
- Allyxycarb (CAS 6392-46-7)
- Diltiazem Impurity N29 Hydrochloride (CAS 42399-54-2)
- Nintedanib Impurity 76 (CAS CATO-C4X-181476)
- Oxacillin Impurity 31 (CAS CATO-C4X-232131)
- 6-Methyl-N1-(3-methyl-1-(6-(methylamino)pyrimidin-4-yl)-1H-pyrazol-5-yl)benzene-1,3-diamine (CAS 1018473-31-8)
- 2,4,6-Tribromo-3,5-difluoropyridine (CAS 30841-93-1)
- 1-(4-([1,1'-Biphenyl]-4-yl)thiazol-2-yl)-4-(thiophen-2-yl)-1H-pyrazol-5-amine (CAS 955964-54-2)
- Daprodustat Impurity 31 (CAS CATO-C4X-240731)
- S(-)-n,n-bis(2-diphenylphosphinoethyl)-1-phenylethylamine (CAS 81510-19-2)
- Benzyl (4-aminocyclohexyl)carbamate (CAS 227017-99-4)
- Allo-D-Ile17-Tirzepatide (CAS CATO-CPTD788962)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com