Niraparib Impurity 3 CAS 1171197-20-8
| CAS No. | 1171197-20-8 |
| Molecular Formula | C16H24N2O2 |
| Molecular Weight | 276.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Niraparib Impurity 3 (CAS 1171197-20-8), a pharmacopoeial impurity reference standard (molecular formula C16H24N2O2, MW 276.37 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Niraparib Impurity 3 (C16H24N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Niraparib Impurity 3 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H24N2O2 |
| Molecular Weight | 276.37 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 2 |
Related Niraparib Standards
- Niraparib Impurity 21 (CAS 1263284-59-8)
- Niraparib Impurity 35 (CAS 1524736-92-2)
- Niraparib Impurity 61 (CAS 3112957-16-8)
- Niraparib Impurity 64 (CAS 2820493-80-7)
- Niraparib Impurity 65 (CAS CATO-C4X-232965)
- Niraparib Impurity 60 (CAS CATO-C4X-232960)
- Niraparib Impurity 49 (CAS 1267209-15-3)
- Niraparib Impurity 48 (CAS 1823263-50-8)
Recommended Standards
- 7,9-Di-tert-butyl-1-oxaspiro[4.5]deca-6,9-diene-2,8-dione (CAS 82304-66-3)
- Cyclandelate (CAS 456-59-7)
- 6-Shogaol (CAS 555-66-8)
- Brivaracetam Impurity 151 (CAS CATO-C4X-2007151)
- Lenvatinib Impurity 157 (CAS CATO-C4X-1140157)
- IMMH-010 Impurity 9 (CAS CATO-C4X-28829)
- Lemborexant Impurity N1 (CAS 1369767-24-7)
- 5,7-Difluoro-2-(pyridin-4-yl)indoline (CAS 591721-09-4)
- 3-Morpholino-4-phenyl-1H-pyrrole-2-carboxylic acid (CAS 135548-45-7)
- Fesoterodine Related Impurity 11 (CAS 194482-42-3)
- 3-Hydroxy-3-methyl-2-butanone (CAS 115-22-0)
- (2-Isopropyltetrahydro-2H-pyran-3-yl)methanamine (CAS 1376435-26-5)
- 2-((3,4-Dimethyl-2-oxo-2h-chromen-7-yl)oxy)propanoic acid (CAS 35679-94-8)
- Semaglutide Impurity 11 (CAS CATO-C4X-222611)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com