Loratadine Impurity 69 CAS 1529-41-5
| CAS No. | 1529-41-5 |
| Molecular Formula | C8H6ClN |
| Molecular Weight | 151.59 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, Loratadine Impurity 69 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 151.59 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Loratadine Impurity 69 (CAS 1529-41-5), a pharmacopoeial impurity reference standard (molecular formula C8H6ClN, MW 151.59 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Loratadine Impurity 69 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6ClN |
| Molecular Weight | 151.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Loratadine Standards
- Loratadine Impurity 7 (CAS 52003-32-4)
- Loratadine Impurity 67 (CAS 29976-54-3)
- Loratadine EP Impurity H (CAS 29976-53-2)
- Loratadine Impurity 66 (CAS 65214-82-6)
- Loratadine Impurity 28 (CAS 1073332-71-4)
- Loratadine Impurity C65 (CAS 51591-52-7)
- Loratadine Impurity 95 (CAS CATO-C4X-142695)
- Loratadine Impurity 71 (CAS CATO-C4X-142671)
Recommended Standards
- Linezolid Impurity 40 (CAS 224323-47-1)
- Letrozole Impurity 29 (CAS 612-13-5)
- Linezolid Impurity 77 (CAS 3920-11-4)
- Letrozole Impurity 30 (CAS 64407-07-4)
- Chlorquinaldol impurity 2 (CAS 13168-78-0)
- Dolutegravir Impurity 56 (CAS CATO-C4X-162056)
- Pimavanserin Impurity 26 (CAS CATO-C4X-193826)
- H-Phe-Leu-Arg-Phe-NH2 (CAS 80690-77-3)
- tert-Butyl (3,5-dichloro-2,6-difluorophenyl)carbamate (CAS 2787600-79-5)
- (2S,4S)-2-methylpiperidine-4-carboxylic acid (CAS 1807937-28-5)
- 2-({5-phenylthieno[2,3-d]pyrimidin-4-yl}sulfanyl)acetic acid (CAS 312947-24-3)
- 3-(3,5-Dimethylphenyl)-3h-[1,2,3]triazolo[4,5-d]pyrimidine-7-thiol (CAS 1082437-15-7)
- 4-(Ethoxycarbonyl)cyclohexanecarboxylic acid (CAS 114478-93-2)
- Semaglutide（sodium salt） (CAS CATO-C4X-222619)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com