Letrozole Impurity 30 CAS 64407-07-4
| CAS No. | 64407-07-4 |
| Molecular Formula | C8H6ClN |
| Molecular Weight | 151.59 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Letrozole Impurity 30 (CAS 64407-07-4), a pharmacopoeial impurity reference standard (molecular formula C8H6ClN, MW 151.59 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Letrozole Impurity 30 (C8H6ClN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Letrozole Impurity 30 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6ClN |
| Molecular Weight | 151.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Letrozole Standards
- Letrozole Impurity 29 (CAS 612-13-5)
- Letrozole Impurity 38 (CAS 874-86-2)
- Letrozole Impurity N2 (CAS 84545-14-2)
- Letrozole Impurity 17 (CAS 112809-27-5)
- Letrozole Impurity 22 (CAS 876728-37-9)
- Letrozole Impurity 23 (CAS 876316-41-5)
- Letrozole Impurity 4 (CAS 112809-25-3)
- Letrozole Impurity 15 (CAS 74231-65-5)
Recommended Standards
- Loratadine Impurity 69 (CAS 1529-41-5)
- Pyrimethamine EP Impurity C (CAS 140-53-4)
- Linezolid Impurity 40 (CAS 224323-47-1)
- Pyrimethamine Impurity 6 (CAS 2856-63-5)
- Pentoxyverine EP Impurity B Hydrochloride (CAS 125-85-9)
- Baloxavir Marboxil Impurity 229 (CAS CATO-C4X-2108229)
- Erlotinib Impurity 90 (CAS 1809951-10-7)
- 4-Bromo-3-iodo-1H-indazol-6-ol (CAS 887568-93-6)
- 7-Bromo-4-(trifluoromethyl)phthalazin-1(2H)-one (CAS 2654746-94-6)
- 3-(bromomethyl)-1,1-dimethoxycyclobutane (CAS 1419101-20-4)
- 1,3-Dimethyl-2-Nitrosobenzene (Mixture of Monomer and Dimer) (CAS 19519-71-2)
- 1-(2,6-Difluorophenyl)cyclopentanamine (CAS 1343777-21-8)
- 6-Butoxy-2-fluoro-3-nitropyridine (CAS 1881321-28-3)
- Tirzepatide Impurity 49 (CAS CATO-C4X-324049)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com