1-Chloro-4-ethoxy-3-fluoro-2-vinylbenzene CAS 167683-92-3
| CAS No. | 167683-92-3 |
| Molecular Formula | C10H10ClFO |
| Molecular Weight | 200.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-Chloro-4-ethoxy-3-fluoro-2-vinylbenzene (CAS 167683-92-3), molecular formula C10H10ClFO and molecular weight 200.64 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-Chloro-4-ethoxy-3-fluoro-2-vinylbenzene (C10H10ClFO) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H10ClFO |
| Molecular Weight | 200.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2004 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 4-(2-Chloro-6-fluorophenyl)butan-2-one (CAS 1019769-64-2)
- 5-Chloro-3-fluoro-2-(pyrrolidin-1-yl)pyridine (CAS 1020253-18-2)
- 5-Chloro-2-thiobenzenesulfonyl fluoride (CAS 108158-05-0)
- 4-(2-Chloro-4-fluorophenyl)butan-2-one (CAS 1099621-26-7)
- 1-(2-Chloro-6-fluorophenyl)butan-2-one (CAS 1178854-65-3)
- (4-Chloro-2-fluorophenyl)(cyclopropyl)methanol (CAS 1202774-93-3)
- 1-(2-Chloro-4-fluorophenyl)butan-2-one (CAS 1248619-92-2)
- 1-(3-Chloro-4-fluorophenyl)-2-methylpropan-1-one (CAS 1266883-86-6)
Recommended Standards
- 4-(but-3-en-1-yloxy)-1-chloro-2-fluorobenzene (CAS 1555645-24-3)
- 2-Chloro-1-(4-fluoro-3,5-dimethylphenyl)ethan-1-one (CAS 176548-89-3)
- 4-(4-Chloro-2-fluorophenyl)butan-2-one (CAS 1540370-13-5)
- 2-(3-Chloro-4-fluorophenyl)-2-methylpropanal (CAS 1785474-13-6)
- Methyl(2-(2-methylallyl)phenyl)sulfane (CAS 951889-18-2)
- Ethyl(4-fluorophenyl)sulfane (CAS 2924-75-6)
- 5-(4-Bromophenyl)-N-(4-chlorophenyl)-1,3,4-thiadiazol-2-amine (CAS 827580-43-8)
- 1-((4-Bromophenyl)(pyridin-2-yl)methyl)piperazine (CAS 512164-34-0)
- 4-(Dimethylsulfamoyl)-1-methyl-1h-pyrrole-2-carboxylic acid (CAS 937613-15-5)
- Glutamic acid impurity 9 (CAS CATO-C4X-28629)
- 1-(Tert-butyl) 3-methyl (R)-azepane-1,3-dicarboxylate (CAS 2382341-27-5)
- 1-(2,3-Dichlorophenyl)-3-(3,4,5-trifluorophenyl)propan-1-one (CAS 898778-51-3)
- N-(5-nitropyridin-2-yl)furan-2-carboxamide (CAS 306766-52-9)
- Semaglutide Impurity 7 (CAS CATO-C4X-22267)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com