Dorzolamide EP Impurity D CAS 154154-90-2
| CAS No. | 154154-90-2 |
| Molecular Formula | C8H12N2O4S3 |
| Molecular Weight | 296.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Dorzolamide EP Impurity D (CAS 154154-90-2), a pharmacopoeial impurity reference standard (molecular formula C8H12N2O4S3, MW 296.39 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Dorzolamide EP Impurity D (C8H12N2O4S3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Dorzolamide EP Impurity D under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H12N2O4S3 |
| Molecular Weight | 296.39 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 3 |
Related Dorzolamide Standards
- Dorzolamide Impurity 8 (CAS 120279-26-7)
- Dorzolamide Impurity 4 (CAS 154802-22-9)
- Dorzolamide Impurity 11 (and enantiomer) (CAS CATO-C4X-122811)
- Dorzolamide (CAS 120279-96-1)
- Rac-Dorzolamide (CAS 120280-13-9)
- Dorzolamide (CAS 139066-77-6)
- Dorzolamide EP Impurity B（R,S-Isomer) (CAS 149249-72-9)
- Dorzolamide EP Impurity A (CAS 120279-95-0)
Recommended Standards
- (E)-2-((4-Methoxybenzylidene)amino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile (CAS 1537173-79-7)
- 5-Ethyl-8-tosyl-2-oxa-5,8-diazaspiro[3.4]Octane (CAS 1556097-47-2)
- N-(Thiophen-2-ylmethyl)-1,9-dioxa-4-azaspiro[5.5]undecane-4-carboxamide (CAS 1421491-17-9)
- (2Z)-3-(2-methylphenyl)-2-[(2-methylphenyl)imino]-1,3-thiazolidin-4-one (CAS 16240-00-9)
- Osimertinib Impurity 70 (CAS CATO-C4X-204570)
- Brimonidine EP Impurity E (CAS 168329-48-4)
- Bifendate impurity N4 (CAS 81474-47-7)
- n-(Sec-butyl)-3-chloro-4-methoxyaniline (CAS 1019572-54-3)
- 4-(Diethylamino)-N-(5-phenyl-1,3,4-oxadiazol-2-yl)butanamide (CAS 89758-22-5)
- 5-Chloro-2,4-dimethylpyridine (CAS 72093-09-5)
- Ethyl 3-oxo-3-(4-propylphenyl)propanoate (CAS 51725-84-9)
- benzyl 2-[bis(tert-butoxycarbonyl)amino]prop-2-enoate (CAS 1798715-69-1)
- 2,6-Difluoro-3-(trifluoromethoxy)benzonitrile (CAS 1806290-43-6)
- D-[Ala]24-Semaglutide (CAS CATO-C4X-2226126)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com