Loratadine Impurity 31 CAS 31255-47-7
| CAS No. | 31255-47-7 |
| Molecular Formula | C13H12ClNO |
| Molecular Weight | 233.69 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Loratadine Impurity 31 (CAS 31255-47-7) is a certified pharmaceutical impurity reference standard with the molecular formula C13H12ClNO and a molecular weight of 233.69 g/mol.
The molecular framework of Loratadine Impurity 31 (C13H12ClNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Loratadine Impurity 31 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H12ClNO |
| Molecular Weight | 233.69 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Loratadine Standards
- Loratadine Impurity B (CAS 38093-12-8)
- Loratadine Impurity 18 (CAS 31255-57-9)
- Loratadine Impurity 74 (CAS 31255-58-0)
- Loratadine EP Impurity B (CAS 31251-41-9)
- Loratadine impurity 85 (CAS 3964-84-9)
- Loratadine impurity 86 (CAS 31251-43-1)
- Loratadine Impurity 90 (CAS 133330-72-0)
- Loratadine Impurity 92 (CAS CATO-C4X-142692)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com