Tolvaptan Impurity 23 CAS 1580889-33-3
| CAS No. | 1580889-33-3 |
| Molecular Formula | C25H23ClN2O3 |
| Molecular Weight | 434.91 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Tolvaptan Impurity 23 (CAS 1580889-33-3), a pharmacopoeial impurity reference standard (molecular formula C25H23ClN2O3, MW 434.91 g/mol) used for the identification and quantification of trace impurities in APIs.
Tolvaptan Impurity 23 (C25H23ClN2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H23ClN2O3 |
| Molecular Weight | 434.91 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Tolvaptan Standards
- Tolvaptan Impurity 24 (CAS 150683-27-5)
- Tolvaptan Impurity 41 (CAS 1580889-32-2)
- Tolvaptan Impurity 99 (CAS 137977-35-6)
- Tolvaptan Impurity 40 (CAS 176970-21-1)
- Tolvaptan Impurity 14 (CAS 137973-76-3)
- Tolvaptan Impurity 67 (CAS 1580889-26-4)
- Tolvaptan Impurity 68 (CAS 1580889-24-2)
- Tolvaptan Impurity 91 (CAS CATO-C4X-195591)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com