Mometasone Impurity 51 CAS CATO-C4X-170451
| CAS No. | CATO-C4X-170451 |
| Molecular Formula | C21H25ClO4 |
| Molecular Weight | 376.87 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Mometasone Impurity 51 (CAS CATO-C4X-170451), a pharmacopoeial impurity reference standard (molecular formula C21H25ClO4, MW 376.87 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Mometasone Impurity 51 (C21H25ClO4) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C21H25ClO4 |
| Molecular Weight | 376.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Mometasone Standards
- Mometasone Impurity C13 (CAS 151265-36-0)
- Mometasone Furoate Impurity 24 (CAS CATO-C4X-170424)
- Mometasone Related Compound 4 (CAS 37413-91-5)
- Mometasone Furoate EP Impurity Q (CAS 83881-08-7)
- Mometasone EP Impurity M (CAS 57780-86-6)
- Mometasone Furoate Impurity 25 (CAS CATO-C4X-170425)
- Mometasone Furoate EP Impurity K (CAS 4647-20-5)
- Mometasone Impurity 28 (CAS CATO-C4X-170428)
Recommended Standards
- (R)-3-Chloro-1-phenyl-1-[2-methyl-4-[(tert-butoxycarbonyl)oxy]phenoxy] propane (CAS 457634-25-2)
- Sarpogrelate Impurity 45 (CAS CATO-C4X-291345)
- ethyl N-[10-(3-chloropropanoyl)phenothiazin-2-yl]carbamate (CAS 34749-22-9)
- Bisphenol A (3-chloro-2-hydroxypropyl) Glycidyl Ether (CAS 13836-48-1)
- Pentazocine Impurity N2 (CAS 58342-26-0)
- Gentamicin Impurity 9 (CAS 287916-51-2 (free base))
- Baloxavir Impurity 3 (CAS 1985606-14-1)
- 4-tert-Butylpyridine-2-carbonitrile (CAS 42205-73-2)
- (+)-Lactacystin (CAS 133343-34-7)
- 2-methoxy-5-(trifluoromethyl)pyridin-3-amine (CAS 944900-42-9)
- 3-Bromopyrazolo[1,5-a]pyrimidine-5-carboxylic acid (CAS 619306-85-3)
- [2-(Benzylsulfanyl)pyrimidin-5-yl]boronic acid (CAS 2342610-74-4)
- rac-(2R,3S)-2-(3-methyl-1,2,4-oxadiazol-5-yl)oxolan-3-amine hydrochloride (CAS 2044705-76-0)
- Tirzepatide Impurity 10 (CAS CATO-C4X-324010)
Why CATO?
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