Vonoprazan Fumarate Impurity 61 CAS 158692-52-5
| CAS No. | 158692-52-5 |
| Molecular Formula | C11H7ClN2 |
| Molecular Weight | 202.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Vonoprazan Fumarate Impurity 61 (C11H7ClN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Vonoprazan Fumarate Impurity 61 (CAS 158692-52-5) is a certified pharmaceutical impurity reference standard with the molecular formula C11H7ClN2 and a molecular weight of 202.64 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Vonoprazan Fumarate Impurity 61 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H7ClN2 |
| Molecular Weight | 202.64 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Vonoprazan Standards
- Vonoprazan Fumarate impurity 1 (CAS 312307-38-3)
- Vonoprazan Impurity 147 (CAS 748810-25-5)
- Vonoprazan Impurity 148 (CAS 2304978-51-4)
- Vonoprazan Impurity 150 (CAS 312307-69-0)
- Vonoprazan Impurity 308 (CAS CATO-C4X-1020308)
- Vonoprazan Impurity 262 (CAS CATO-C4X-1020262)
- Vonoprazan Impurity 217 (CAS 16420-39-6)
- Vonoprazan Impurity 103 (CAS CATO-C4X-1020103)
Recommended Standards
- Methyl 2-(1-chloroethyl)-1-methyl-1H-imidazole-5-carboxylate (CAS 2734876-13-0)
- 1-(2-Chloro-6-fluorophenyl)butan-2-ol (CAS 1247196-94-6)
- Ethyl 5-chloro-1,3-dimethyl-1H-pyrazole-4-carboxylate (CAS 85290-72-8)
- 1-(2-Chloro-6-fluorophenyl)-2-methylpropan-2-ol (CAS 1249273-13-9)
- Clindamycin Phosphate Impurity 12 HCl (CAS 1800297-64-6)
- Ketorolac EP Impurity C (CAS 1026936-07-1)
- Ponatinib impurity 6 (CAS 2227480-51-3)
- 4-Bromotetrafluorophenol (CAS 1998-61-4)
- Methyl (Z)-2-chloro-2-(2-(4-chlorophenyl)hydrazono)acetate (CAS 62465-90-1)
- 1-(2,5-Dichlorobenzyl)-N-methylpiperidin-4-amine hydrochloride (CAS 1289385-68-7)
- Pz-Pro-Leu-Gly-Pro-D-Arg-OH (CAS 17011-78-8)
- 1-(3-Methoxy-phenyl)-5-oxo-pyrrolidine-3-carbonyl chloride (CAS 1239777-93-5)
- 3-(3-Amino-5,6-dihydrocyclopenta[c]pyrazol-2(4H)-yl)tetrahydrothiophene 1,1-dioxide (CAS 1428234-06-3)
- Anti-Inflammatory Peptide 1 (CAS 118850-71-8)
Why CATO?
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