Letrozole Impurity 27 CAS 160388-64-7
| CAS No. | 160388-64-7 |
| Molecular Formula | C12H13N3O2 |
| Molecular Weight | 231.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Letrozole Impurity 27 (CAS 160388-64-7), a pharmacopoeial impurity reference standard (molecular formula C12H13N3O2, MW 231.25 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Letrozole Impurity 27 (C12H13N3O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Letrozole Impurity 27 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H13N3O2 |
| Molecular Weight | 231.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Nitrogen Atoms | 3 |
Related Letrozole Standards
- Letrozole Impurity 5 (CAS 32446-66-5)
- Letrozole Impurity 6 (CAS 134521-16-7)
- Letrozole Impurity 14 (CAS 2451658-74-3)
- Letrozole impurity 01 (CAS 10466-37-2)
- Letrozole Impurity 26 (CAS 870766-45-3)
- Letrozole Impurity 32 (CAS 305861-48-7)
- Letrozole Impurity 25 (CAS 1250126-45-4)
- Letrozole Impurity 24 (CAS CATO-C4X-182924)
Recommended Standards
- Iguratimod Impurity 126 (CAS CATO-C4X-1826126)
- Phenobarbital Impurity6 (CAS 130690-55-0)
- Procaterol Impurity 58 (CAS CATO-C4X-181058)
- Alanyl Glutamine Impurity 16 (CAS 672284-92-3)
- Tebipenem Impurity 13 (CAS CATO-C4X-134713)
- Hyoscyamine Impurity 7 (CAS CATO-C4X-34377)
- Trazodone impurity 40 (CAS 328410-01-1)
- 2,2,5-Trimethyl-2,3-dihydrobenzofuran-7-amine (CAS 95579-84-3)
- (2-Nitrobenzyl)triphenylphosphoniumchloride (CAS 52513-28-7)
- UDP-Rhamnose (CAS 1955-26-6)
- (4-methylpyridin-2-yl)(oxan-4-yl)methanamine dihydrochloride (CAS 2044714-06-7)
- (1R,3R)-Cyclohexane-1,3-dicarboxylic acid (CAS 21917-23-7)
- 2-(Carbamoylamino)-2-phenylacetic acid (CAS 82264-50-4)
- Pancreatic Polypeptide (31-36) Free Acid, human (CAS 192432-73-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com