Lamivudine EP Impurity H CAS 160552-54-5
| CAS No. | 160552-54-5 |
| Molecular Formula | C8H11N3O4S |
| Molecular Weight | 245.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Lamivudine EP Impurity H (CAS 160552-54-5), a pharmacopoeial impurity reference standard (molecular formula C8H11N3O4S, MW 245.26 g/mol) used for the identification and quantification of trace impurities in APIs.
Lamivudine EP Impurity H (C8H11N3O4S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H11N3O4S |
| Molecular Weight | 245.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Lamivudine Standards
- Lamivudine Impurity 1 (CAS 1235712-40-9)
- Lamivudine Impurity 18 (CAS CATO-C4X-119418)
- Lamivudine EP Impurity G (CAS 160552-55-6)
- Lamivudine Impurity 43 (CAS CATO-C4X-119443)
- Lamivudine Impurity 44 (CAS CATO-C4X-119444)
- Lamivudine Acid-13C,15N2 (CAS 1391052-30-4)
- Lamivudine EP impurity A (CAS 173602-25-0)
- Lamivudine EP Impurity A(2R,5S)Monomer (CAS 173829-09-9)
Recommended Standards
- Emtricitabine Impurity 35 (CAS 1238210-14-4)
- Ro 106-9920 (CAS 62645-28-7)
- N-Nitroso Piperacillin impurity 102 (CAS CATO-C4X-1732102)
- N-Methyl-4-(methylamino)-3-nitrobenzenesulfonamide (CAS 68502-28-3)
- Vildagliptin Impurity 87 (CAS 1789703-37-2)
- Mitiglinide Impurity 28 (CAS CATO-C4X-116128)
- Cefuroxime Impurity 88 (CAS CATO-C4X-124588)
- (E)-3-((4-(2,4-dichlorostyryl)pyrimidin-2-yl)thio)-5-(trifluoromethyl)picolinamide (CAS 338968-24-4)
- 8-(2,3,4-Trimethoxyphenyl)-8-oxooctanoic acid (CAS 951892-06-1)
- 3-(Hexylthio)-1H-1,2,4-triazole (CAS 74682-60-3)
- 2-Amino-1-(3-fluorophenyl)ethanone hydrochloride (CAS 93102-97-7)
- Tert-butyl 3-formyl-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8h)-carboxylate (CAS 1174069-03-4)
- Ethyl N-methyl-N-(2-(trifluoromethyl)quinazolin-4-yl)glycinate (CAS 1208081-16-6)
- Renin Inhibitor Peptide (CAS 50410-01-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com