Lamivudine Impurity 43 CAS CATO-C4X-119443
| CAS No. | CATO-C4X-119443 |
| Molecular Formula | C8H11N3O4S |
| Molecular Weight | 245.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C8H11N3O4S, Lamivudine Impurity 43 contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 245.26 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Lamivudine Impurity 43 (CAS CATO-C4X-119443, C8H11N3O4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H11N3O4S |
| Molecular Weight | 245.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Lamivudine Standards
- Lamivudine Impurity 1 (CAS 1235712-40-9)
- Lamivudine Impurity 18 (CAS CATO-C4X-119418)
- Lamivudine EP Impurity G (CAS 160552-55-6)
- Lamivudine EP Impurity H (CAS 160552-54-5)
- Lamivudine Impurity 44 (CAS CATO-C4X-119444)
- Lamivudine Acid-13C,15N2 (CAS 1391052-30-4)
- Lamivudine EP impurity A (CAS 173602-25-0)
- Lamivudine EP Impurity A(2R,5S)Monomer (CAS 173829-09-9)
Recommended Standards
- Emtricitabine Impurity 35 (CAS 1238210-14-4)
- N-Nitroso Piperacillin impurity 102 (CAS CATO-C4X-1732102)
- (3R,4R)-3-((tert-Butoxycarbonyl)amino)tetrahydro-2h-pyran-4-carboxylicacid (CAS 1006891-33-3)
- Ro 106-9920 (CAS 62645-28-7)
- Spironolactone EP Impurity G (CAS 880106-10-5)
- Crotonic Acid Impurity 1 (Butyl 3-Formyl-Crotonate) (CAS 40212-97-3)
- Istradefylline impurity 36 (CAS CATO-C4X-106136)
- Tryptophan impurity 32 (CAS 2306500-74-1)
- 2-Fluoro-5-(2-trifluoromethylphenyl)benzoic acid (CAS 1261772-06-8)
- Rivaroxaban Impurity 43 (CAS 1369969-44-7)
- 5-(Hydroxymethyl)-N-mesitylisoxazole-3-carboxamide (CAS 145440-90-0)
- 4,5,6,7-Tetrahydro-2H-indazol-6-amine dihydrochloride (CAS 74197-26-5)
- CAS 2260670-62-8 (CAS 2260670-62-8)
- Semaglutide impurity 44 (CAS CATO-C4X-222644)
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