Propofol Impurity 32 CAS 161070-01-5
| CAS No. | 161070-01-5 |
| Molecular Formula | C13H18O3 |
| Molecular Weight | 222.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Propofol Impurity 32 (CAS 161070-01-5, C13H18O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C13H18O3, Propofol Impurity 32 contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 222.28 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H18O3 |
| Molecular Weight | 222.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
Related Propofol Standards
- Propofol Impurity 21 (CAS 153752-00-2)
- Propofol EP Impurity N (CAS 13423-73-9)
- Propofol Impurity 33 (CAS CATO-C4X-147333)
- Propofol Impurity 35 (CAS 2215-21-6)
- Propofol Impurity 39 (CAS 100482-27-7)
- Propofol Impurity 46 (CAS CATO-C4X-147346)
- Propofol Impurity 48 (CAS CATO-C4X-147348)
- Propofol Impurity 59 (CAS CATO-C4X-147359)
Recommended Standards
- Glipizide Impurity 37 (CAS 350983-37-8)
- Sunitinib Impurity 13 (CAS 1309935-09-8)
- Aclidinium bromide Impurity 2 (CAS 7333-07-5)
- Perindopril EP Impurity K (CAS 2165676-00-4)
- Orforglipron Impurity 48 (CAS CATO-C4X-323448)
- Lornoxicam Impurity 23 (CAS CATO-C4X-201623)
- Benidipine Impurity 76 (CAS CATO-C4X-112076)
- Famotidine Impurity 84 (CAS CATO-C4X-139284)
- Methyl 7-bromo-2,3-dihydro-1H-indene-5-carboxylate (CAS 2090004-40-1)
- 2-(Methylthio)-N-octylquinazolin-4-amine (CAS 866137-97-5)
- Ethyl 2-aminooxazole-4-carboxylate (CAS 177760-52-0)
- (S)-2-(3-Chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-6-methyl-4-(5-methyl-1,1-dioxido-1,2,5-thiadiazolidin-2-yl)-7,8-dihydropyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-1,9(2H,6H)-dione (CAS 1334669-63-4)
- 4-Imino-1-oxa-3-azaspiro[4.4]nonan-2-one (CAS 1692817-87-0)
- Semaglutide impurity 94 (CAS CATO-C4X-222694)
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