Tenofovir Impurity 37 CAS 161760-03-8
| CAS No. | 161760-03-8 |
| Molecular Formula | C10H15O6PS |
| Molecular Weight | 294.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Tenofovir Impurity 37 (CAS 161760-03-8) is a certified pharmaceutical impurity reference standard with the molecular formula C10H15O6PS and a molecular weight of 294.26 g/mol.
Tenofovir Impurity 37 (C10H15O6PS) contains a sulfone group, a phosphate ester group, a carboxylic acid group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Tenofovir Impurity 37 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H15O6PS |
| Molecular Weight | 294.26 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2003 |
| Sulfur Atoms | 1 |
Related Tenofovir Standards
- rac-Tenofovir-d7 (CAS CATO-C4X-107643)
- Tenofovir-d (CAS 1217720-14-3)
- rac Tenofovir-d6 (CAS 1020719-94-1)
- Tenofovir ImineDISCONTINUED (CAS 1962114-85-7)
- Tenofovir disoproxil Impurity 109 (CAS CATO-C4X-1076109)
- Tenofovir Monomethyl Ester (CAS 1796539-83-7)
- rac-Tenofovir (CAS 2667563-23-5)
- Tenofovir disoproxil Impurity 105 (CAS 2361988-22-7)
Recommended Standards
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- Methotrexate Impurity 44 (CAS 93528-16-6)
- Nω-(β-D-Mannopyranosyl)-L-asparagine (CAS 41355-52-6)
- Azithromycin Impurity 32 (CAS CATO-C4X-100332)
- Melphalan Impurity 32 (CAS CATO-C4X-198832)
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- 1704120-79-5 (4-((4-(2-Hydroxyethyl)piperazin-1-yl)sulfonyl)-3,5-dimethylphenyl)boronic acid MFCD28805576 (CAS 1704120-79-5)
- 2-(2,4-Dichlorophenyl)-1-methoxy-1H-imidazo[4,5-b]pyridine (CAS 338978-54-4)
- Ethyl 2-(4-methoxyphenoxy)propanoate (CAS 111479-08-4)
- oxazol-2-yl(phenyl)methanol (CAS 130552-00-0)
- 1-(2-Ethyl-2-hydroxybutyl)-3-(2-fluorophenyl)urea (CAS 1252363-31-7)
- 1-[1-methyl-7-(piperazin-1-yl)-1H-indol-4-yl]-1,3-diazinane-2,4-dione (CAS 2766179-64-8)
- Tau Peptide (268-282) trifluoroacetate salt (CAS 330456-37-6)
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