Roflumilast CAS 162401-32-3
| CAS No. | 162401-32-3 |
| Molecular Formula | C17H14Cl2F2N2O3 |
| Molecular Weight | 403.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C17H14Cl2F2N2O3, Roflumilast contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 403.21 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Roflumilast (CAS 162401-32-3), molecular formula C17H14Cl2F2N2O3 and molecular weight 403.21 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H14Cl2F2N2O3 |
| Molecular Weight | 403.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Roflumilast Standards
- Roflumilast Impurity 1 (CAS 162401-43-6)
- Roflumilast Impurity 29 (CAS 2368178-28-1)
- Roflumilast Impurity 53 (CAS 2204417-23-0)
- Roflumilast-d3 (CAS 1189992-00-4)
- Roflumilast -D4 (CAS 1398065-69-4)
- Roflumilast Impurity 6 (CAS 2368178-29-2)
- Roflumilast Impurity 3 (CAS 1391052-24-6)
- Roflumilast Impurity 4 (CAS 162401-30-1)
Recommended Standards
- Tributyl(5-methoxythiophen-2-yl)stannane (CAS 879480-43-0)
- Diethyl 2-(((4-iodo-2-methylphenyl)-amino)methylene)malonate (CAS 951006-38-5)
- Diethyl ((4-bromo-2-methyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-3-yl)methyl)phosphonate (CAS 54813-89-7)
- 6,7-Dichloro-2,4-bis(4-fluorophenyl)phthalazin-1(2H)-one (CAS 339009-77-7)
- (3aR,7aS)-1,3-Dimethyl-2-(piperidin-1-yl)octahydro-1H-benzo[d][1,3,2]diazaphosphole 2-oxide (CAS 161390-52-9)
- tert-Butyl (S)-2-(5-(6-bromonaphthalen-2-yl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate (CAS 1228551-96-9)
- Ethyl 2-(2-morpholinoacetamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 62349-05-7)
- 6-(Difluoromethyl)pyridin-2(1H)-one (CAS 195044-11-2)
- Octyl-α-ketoglutarate (CAS 876150-14-0)
- 6-(Cyclohexylthio)-5-methylnicotinonitrile (CAS 1355177-88-6)
- 2-(2,4-Dimethylphenoxy)ethan-1-amine (CAS 50912-65-7)
- Boc-(1S,2R)-(+)-2-aminocyclohex-4-ene-carboxylicacid (CAS 1226812-50-5)
- Methyl(tosylmethyl)sulfane (CAS 59662-65-6)
- Neuropeptide Y (13-36) (porcine) (CAS 113662-54-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com