Empagliflozin impurity 56 CAS 1628918-33-1
| CAS No. | 1628918-33-1 |
| Molecular Formula | C13H9BrClF |
| Molecular Weight | 299.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Empagliflozin impurity 56 is closely related to fluorine/chlorine/bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Empagliflozin impurity 56 (CAS 1628918-33-1, C13H9BrClF) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to fluorine/chlorine/bromine substitution, an aromatic ring system, Empagliflozin impurity 56 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 299.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Empagliflozin impurity 56 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H9BrClF |
| Molecular Weight | 299.57 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F/Cl/Br-containing |
Related Empagliflozin Standards
- Empagliflozin impurity 260 (CAS CATO-C4X-1065260)
- Empagliflozin Impurity 90 (CAS 620621-48-9)
- Empagliflozin Impurity 154 (CAS 2452301-22-1)
- Empagliflozin Impurity 03 (CAS 312749-31-8)
- Empagliflozin Impurity 310 (CAS CATO-C4X-1065310)
- Empagliflozin Impurity 4 (CAS 2770456-61-4)
- Empagliflozin Impurity 46 (CAS CATO-C4X-106546)
- Empagliflozin Impurity 281 (CAS 1096342-71-0)
Recommended Standards
- Oleic Acid-d17 (CAS 223487-44-3)
- 5-Bromo-6-chloro-N-ethylpyridine-3-sulfonamide (CAS 622814-98-6)
- 4,6-Dichloro-5-(2-chlorophenyl)-2-cyclopropylpyrimidine (CAS 1523025-65-1)
- 5-Bromo-2-methoxy-4-methylbenzenesulfonyl chloride (CAS 808134-00-1)
- Empagliflozin impurity 229 (CAS CATO-C4X-1065229)
- Dalilesen Impurity 11 (CAS CATO-C4X-301011)
- Methocarbamol Impurity 11 (CAS CATO-C4X-244411)
- 4'-((2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl)-N-(4,5-dimethylisoxazol-3-yl)-2'-(ethoxymethyl)-N-(methoxymethyl)-[1,1'-biphenyl]-2-sulfonamide (CAS 1026355-73-6)
- Ethyl 2-amino-4-bromothiazole-5-carboxylate (CAS 1353102-10-9)
- Melphalan Impurity 26 (CAS CATO-C4X-198826)
- 2,6-Difluoro-3-methoxybenzenesulfonyl chloride (CAS 1706458-18-5)
- 2-Phenylhept-6-enoic acid (CAS 115420-26-3)
- 1-Aminobenzo[d]isothiazol-3-one 1-oxide (CAS 2097006-10-3)
- Neuropeptide K, porcine (CAS 106441-70-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com