Mavacamten Impurity 8 CAS 1642289-11-9
| CAS No. | 1642289-11-9 |
| Molecular Formula | C9H14N2O3 |
| Molecular Weight | 198.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Mavacamten Impurity 8.
Mavacamten Impurity 8 (CAS 1642289-11-9) is a certified pharmaceutical impurity reference standard with the molecular formula C9H14N2O3 and a molecular weight of 198.22 g/mol.
Mavacamten Impurity 8 (C9H14N2O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Mavacamten Impurity 8 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H14N2O3 |
| Molecular Weight | 198.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Nitrogen Atoms | 2 |
Related Mavacamten Standards
- Mavacamten Impurity 6 (CAS CATO-C4X-29826)
- Mavacamten Intermediates Impurity 1 (CAS 887581-47-7)
- Mavacamten Impurity 10 (CAS 1642289-54-0)
- Mavacamten Impurity 2 (CAS CATO-C4X-29822)
- Mavacamten Impurity 3 (CAS CATO-C4X-29823)
- Mavacamten Impurity 7 (CAS 66400-12-2)
- Mavacamten Impurity 15 (CAS 30221-94-4)
- Mavacamten Impurity 9 (CAS 67463-81-4)
Recommended Standards
- Mirogabalin Imputity 101 (CAS CATO-C4X-2924101)
- 2-Amino-3-methyl-3H-imidazo[4,5-f]quinoline (CAS 76180-96-6)
- Metharbital (CAS 50-11-3)
- Henyl Benzoate (CAS 93-99-2)
- Beclometasone Dipropionate Monohydrate EP Impurity U (CAS 79578-39-5)
- Bumetanide Impurity 77 (CAS CATO-C4X-198677)
- Oseltamivir impurity 276 (CAS 2413185-98-3)
- 2-Ethyl-4-(2,2,2-trifluoroethyl)aniline (CAS 476335-33-8)
- 4-(6,7-Dimethoxyquinazolin-4-yl)-N-(4-nitrophenyl)piperazine-1-carboxamide (CAS 205255-11-4)
- 1-Phenyl-2-((5-phenyl-1,3,4-oxadiazol-2-yl)thio)ethanone (CAS 74087-90-4)
- 3-(6-(2-Fluorobenzoyl)-2-oxobenzo[d]oxazol-3(2H)-yl)propanoic acid (CAS 648410-54-2)
- tert-Butyl N-cyclopropyl-N-(3-hydroxypropyl)carbamate (CAS 155541-96-1)
- 2-(2-(Difluoromethyl)-5,6-difluoropyridin-3-yl)acetic acid (CAS 1806823-11-9)
- D-Gln24-Tirzepatide (CAS CATO-CPTD788910)
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