5-Bromo-7-chloro-2-(4-chlorophenyl)-1H-benzo[d]imidazole CAS 16429-36-0

Purity 97%+In StockPharmaceutical Standards
CAS No.16429-36-0
Molecular FormulaC13H7BrCl2N2
Molecular Weight342.02 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Bromo-7-chloro-2-(4-chlorophenyl)-1H-benzo[d]imidazole CAS 16429-36-0 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Bromo-7-chloro-2-(4-chlorophenyl)-1H-benzo[d]imidazole.

5-Bromo-7-chloro-2-(4-chlorophenyl)-1H-benzo[d]imidazole (CAS 16429-36-0) is a high-purity analytical reference standard with the molecular formula C13H7BrCl2N2 and a molecular weight of 342.02 g/mol.

Structurally, 5-Bromo-7-chloro-2-(4-chlorophenyl)-1H-benzo[d]imidazole (C13H7BrCl2N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 342.02 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC13H7BrCl2N2
Molecular Weight342.02 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1961
Halogen ContentCl/Br-containing
Nitrogen Atoms2

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