Ketoconazole impurity 31 CAS CATO-C4X-147231
| CAS No. | CATO-C4X-147231 |
| Molecular Formula | C11H11BrCl2O3 |
| Molecular Weight | 342.01 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Ketoconazole impurity 31 (CAS CATO-C4X-147231), a pharmacopoeial impurity reference standard (molecular formula C11H11BrCl2O3, MW 342.01 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C11H11BrCl2O3, Ketoconazole impurity 31 contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 342.01 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures Ketoconazole impurity 31 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H11BrCl2O3 |
| Molecular Weight | 342.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl/Br-containing |
Related Ketoconazole Standards
- Ketoconazole Impurity 8 (Mixture of diastereomers) (CAS 68751-57-5)
- Ketoconazole Impurity 38 (CAS 24123-68-0)
- Ketoconazole Impurity 20 (CAS CATO-C4X-147220)
- Ketoconazole Impurity 10 (CAS 61441-65-4)
- Ketoconazole Impurity 11 (CAS 84682-23-5)
- Ketoconazole Impurity 13 (and enantiomer) (CAS 61397-58-8)
- Ketoconazole Impurity 14 (CAS 170210-49-8)
- Ketoconazole Impurity 35 (CAS CATO-C4X-147235)
Recommended Standards
- 7-Bromo-4,6-dichloro-8-fluoro-2-(methylthio)quinazoline (CAS 2757097-20-2)
- 7-Bromo-2,6-dichloro-8-fluoro-4-(methylthio)quinazoline (CAS 2857929-87-2)
- 7-Bromo-5-chloro-2-(4-chlorophenyl)-1H-benzo[d]imidazole (CAS 16429-30-4)
- Methyl 5-(2,2-dibromoacetyl)thiophene-2-carboxylate (CAS 656227-47-3)
- Drotaverin Impurity 60 (CAS CATO-C4X-243560)
- Oseltamivir Impurity N7 (CAS 1376142-56-1)
- Sitagliptin Impurity 163 (CAS 2945884-76-2)
- N'-((1,3-Diphenyl-1H-pyrazol-4-yl)methylene)-3-methyl-1-phenyl-1H-thieno[2,3-c]pyrazole-5-carbohydrazide (CAS 402840-88-4)
- 1-(4-Nitrophenyl)-N-(p-tolyl)methanimine (CAS 730-39-2)
- 2-Bromo-1-ethoxy-4-(trifluoromethoxy)benzene (CAS 200956-50-9)
- 5-Methyl-1-(4-nitrophenyl)-1H-pyrazol-3(2H)-one (CAS 58332-40-4)
- 6-Bromo-4-nitro-1H-indazole-3-carbaldehyde (CAS 885518-61-6)
- 4-Methoxy-1-(prop-2-yn-1-yl)piperidine (CAS 1219606-37-7)
- Tau Peptide (74-102) (Exon 3/Insert 2 Domain) trifluoroacetate salt (CAS 1322695-34-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com