Famotidine Impurity 65 CAS 1644079-28-6
| CAS No. | 1644079-28-6 |
| Molecular Formula | C5H7ClN4S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Famotidine Impurity 65 (CAS 1644079-28-6), a pharmacopoeial impurity reference standard (molecular formula C5H7ClN4SHCl, MW 227.11 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrile group, sulfur-containing functionality, chlorine substitution, Famotidine Impurity 65 is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 227.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H7ClN4S HCl |
| Molecular Weight | 227.11 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Famotidine Standards
- Famotidine impurity HCl, >98% (CAS 100599-91-5)
- Famotidine EP Impurity I (CAS 1020719-36-1)
- Famotidine EP Impurity C (CAS 106433-44-7)
- Famotidine Impurity 23 (CAS 106649-95-0)
- Famotidine EP Impurity H (CAS 106649-96-1)
- Famotidine EP Impurity F (CAS 107880-74-0)
- Famotidine EP Impurity B Dimaleate (CAS 109467-08-5)
- Famotidine impurity 01 (CAS 1185040-73-6)
Recommended Standards
- Dapagliflozin Impurity N50 (CAS 21900-52-7)
- Prednisolone impurity 66 (CAS 137759-50-3)
- Teprenone Impurity 6 (CAS 70851-60-4)
- 2-(Benzyloxy)-5-bromophenol (CAS 153241-03-3)
- 4-((3-Bromobenzyl)oxy)-3-methoxybenzaldehyde (CAS 667437-49-2)
- 1-Butylcarbamoyl-5-Fluorouracil (CAS 64098-82-4)
- 2,2'-((Propane-1,2-diylbis(oxy))bis(methylene))bis(oxirane) (CAS 16096-30-3)
- Ammonium dodecanedioate (CAS 59864-79-8)
- 5-Bromo-3-chloro-N-(2,2-dimethylthietan-3-yl)pyridin-2-amine (CAS 1870100-35-8)
- Liraglutide(13-31)TFA Salt (CAS CATO-C4X-19929)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com