Neostigmine Impurity 50 CAS 16460-28-9
| CAS No. | 16460-28-9 |
| Molecular Formula | C15H16N2O3 |
| Molecular Weight | 272.30 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Neostigmine Impurity 50 (C15H16N2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Neostigmine Impurity 50 (CAS 16460-28-9), a pharmacopoeial impurity reference standard (molecular formula C15H16N2O3, MW 272.30 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Neostigmine Impurity 50 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H16N2O3 |
| Molecular Weight | 272.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 2 |
Related Neostigmine Standards
- Neostigmine Impurity 1 (CAS CATO-C4X-20421)
- Neostigmine Impurity N1 (CAS 2434689-89-9)
- Neostigmine Impurity 27 (CAS 63468-95-1)
- Neostigmine impurity 41 (CAS CATO-C4X-204241)
- Neostigmine impurity 42 (CAS CATO-C4X-204242)
- Neostigmine Impurity 51 (CAS 867020-61-9)
- Neostigmine Impurity 13 (CAS 4939-59-7)
- Neostigmine impurity 47 (CAS CATO-C4X-204247)
Recommended Standards
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- Urapidil Impurity 22 (CAS CATO-C4X-192422)
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- Etrasimod Impurity 78 (CAS CATO-C4X-321478)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com