Neostigmine Impurity 51 CAS 867020-61-9

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.867020-61-9
Molecular FormulaC16H20N2O
Molecular Weight256.34 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Neostigmine Impurity 51 CAS 867020-61-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 256.34 g/mol gives Neostigmine Impurity 51 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Neostigmine Impurity 51 (CAS 867020-61-9), a pharmacopoeial impurity reference standard (molecular formula C16H20N2O, MW 256.34 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C16H20N2O, Neostigmine Impurity 51 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 256.34 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Neostigmine Impurity 51 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC16H20N2O
Molecular Weight256.34 g/mol
Purity≥95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Nitrogen Atoms2

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