Cetirizine EP Impurity G Hydrochloride CAS 164726-80-1
| CAS No. | 164726-80-1 |
| Molecular Formula | C19H23ClN2O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 367.31 g/mol gives Cetirizine EP Impurity G Hydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Cetirizine EP Impurity G Hydrochloride (CAS 164726-80-1), a pharmacopoeial impurity reference standard (molecular formula C19H23ClN2OHCl, MW 367.31 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Cetirizine EP Impurity G Hydrochloride is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 367.31 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Cetirizine EP Impurity G Hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H23ClN2O 2*HCl |
| Molecular Weight | 367.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2004 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Cetirizine Standards
- Cetirizine EP Impurity B (CAS 1000690-91-4)
- Cetirizine Impurity 10 (CAS 1016-78-0)
- rac Cetirizine N-Oxide (Mixture of Diastereomers) (CAS 1076199-80-8)
- Cetirizine USP Related Compound B (CAS 108983-83-1)
- Cetirizine EP Impurity G (CAS 109806-71-5)
- (R)-Cetirizine-d4 Dihydrochloride (CAS 1133210-23-7)
- Cetirizine Impurity N19 (CAS 113740-61-7)
- rac Cetirizine-d8 N-Oxide (CAS 1216444-13-1)
Recommended Standards
- Olaparib Impurity 60 (CAS CATO-C4X-113560)
- Simvastatin Impurity 27 (CAS 132487-01-5)
- Loratadine Impurity 50 (CAS CATO-C4X-142650)
- 3-(2,4-Dichlorophenyl)-3-hydroxypropanenitrile (CAS 868135-74-4)
- Fosfomycin Impurity 29 (CAS CATO-C4X-131629)
- 2-Propylthiazolidine-4-carboxylic acid (CAS 4165-34-8)
- (3S,4R)-4-(3-fluorophenyl)-1-(2-methoxyethyl)pyrrolidin-3-amine (CAS 1414836-90-0)
- 1-(4-Fluorobenzyl)-1h-indole-2,3-dione (CAS 313245-18-0)
- (3R,4S)-4-Aminotetrahydrothiophen-3-ol hydrochloride (CAS 30461-27-9)
- Peptide 433 (CAS CATO-CPTD788433)
Why CATO?
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