Loratadine Impurity 50 CAS CATO-C4X-142650
| CAS No. | CATO-C4X-142650 |
| Molecular Formula | C32H44ClN3O4 |
| Molecular Weight | 570.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Loratadine Impurity 50 (C32H44ClN3O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Loratadine Impurity 50 (CAS CATO-C4X-142650) is a certified pharmaceutical impurity reference standard with the molecular formula C32H44ClN3O4 and a molecular weight of 570.16 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Loratadine Impurity 50 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C32H44ClN3O4 |
| Molecular Weight | 570.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Loratadine Standards
- Loratadine Impurity 52 (CAS CATO-C4X-142652)
- Loratadine glucose adduct (CAS CATO-C4X-142640)
- Loratadine glucose adduct (CAS CATO-C4X-142673)
- Loratadine Impurity 62 (CAS CATO-C4X-142662)
- Loratadine Impurity 64 (CAS CATO-C4X-142664)
- Loratadine Impurity 58 (CAS CATO-C4X-142658)
- Loratadine Impurity 46 (CAS CATO-C4X-142646)
- Loratadine Impurity 60 (CAS CATO-C4X-142660)
Recommended Standards
- Montelukast EP Impurity F (CAS 937275-23-5)
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- Betacarotene impurity 12 (CAS CATO-C4X-281512)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com