Chlorhexidine EP Impurity G DiHCl CAS 165678-61-5
| CAS No. | 165678-61-5 |
| Molecular Formula | C14H23ClN6 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Chlorhexidine EP Impurity G DiHCl is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Chlorhexidine EP Impurity G DiHCl (CAS 165678-61-5) is a certified pharmaceutical impurity reference standard with the molecular formula C14H23ClN6HCl and a molecular weight of 347.29 g/mol.
Structurally, Chlorhexidine EP Impurity G DiHCl (C14H23ClN6HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 347.29 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Chlorhexidine EP Impurity G DiHCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H23ClN6 2*HCl |
| Molecular Weight | 347.29 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2004 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
Related Chlorhexidine Standards
- Chlorhexidine-d8 Dihydrochloride (CAS 1246816-96-5)
- Chlorhexidine Diacetate EP Impurity B (CAS 1308292-89-8)
- Chlorhexidine EP Impurity K HCI (CAS 1381962-77-1（free base）)
- Chlorhexidine EP Impurity A (CAS 152504-08-0)
- Chlorhexidine EP Impurity A Hydrochloride (CAS 152504-08-0（free base）)
- Chlorhexidine Digluconate EP Impurity G HCl (CAS 152504-09-1 (free base))
- Chlorhexidine EP Impurity N (CAS 152504-10-4)
- Chlorhexidine Diacetate Impurity 2 Hydrochloride (CAS 152504-10-4(Free Base))
Recommended Standards
- Lamotrigine EP Impurity G (CAS 38943-76-9)
- Empagliflozin Impurity 29 (CAS 86728-85-0)
- Flunarizine Impurity 18 (CAS CATO-C4X-135718)
- 2-(2-(2-(3-Fluorophenyl)thiazol-4-yl)ethyl)isoindoline-1,3-dione (CAS 250258-58-3)
- 3-{[4-(2,6-difluorobenzoyl)-3-methyl-2-oxo-1,2,3,4-tetrahydroquinoxalin-1-yl]methyl}benzonitrile (CAS 317833-44-6)
- 2217-40-5 O7A3GV2PNX 1-Aminotetralin 1,2,3,4-Tetrahydro-1-naphthylamine EINECS 218-712-7 NSC 30349 EC 218-712-7 UNII-O7A3GV2PNX (CAS 2217-40-5)
- (3-Aminopropyl)(difluoromethyl)phosphinic acid (CAS 133345-73-0)
- 4,4'-Bipyridine dihydrate (CAS 87378-14-1)
- (2'-Cyano-2-fluoro-[1,1'-biphenyl]-3-yl)boronic acid (CAS 425378-90-1)
- Neuroendocrine Regulatory Peptide-1 (human) (H-6622.1000) (CAS 954420-50-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com