Agomelatine Impurity 7 CAS 166526-99-4
| CAS No. | 166526-99-4 |
| Molecular Formula | C15H17NO3 |
| Molecular Weight | 259.30 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Agomelatine Impurity 7 (CAS 166526-99-4), a pharmacopoeial impurity reference standard (molecular formula C15H17NO3, MW 259.30 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Agomelatine Impurity 7 (C15H17NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Agomelatine Impurity 7 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H17NO3 |
| Molecular Weight | 259.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2004 |
| Nitrogen Atoms | 1 |
Related Agomelatine Standards
- Agomelatine Impurity 32 (CAS 138112-79-5)
- Agomelatine Impurity 19 (CAS 99416-97-4)
- Agomelatine-d6 (CAS 1079389-42-6)
- Agomelatine Impurity 35 (CAS 178677-49-1)
- Agomelatine Impurity 28 (CAS CATO-C4X-110828)
- Agomelatine-D3 (CAS 107389-38-0)
- Agomelatine Impurity 53 (CAS CATO-C4X-110853)
- Agomelatine Impurity 19 (CAS 1352139-51-5)
Recommended Standards
- Milrinone Impurity 16 (CAS 2244529-59-5)
- Dobutamine Impurity 54 (CAS CATO-C4X-129854)
- Milrinone Impurity 15 (CAS CATO-C4X-109115)
- Norepinephrine Impurity 128 (CAS 2504336-93-8)
- Dexamethasone impurity 65 (CAS 1202002-01-4)
- Vilanterol Impurity 46 (CAS CATO-C4X-193546)
- Bixalomer Impurity 1 (CAS 120239-62-5)
- Methyl 3-(3-chlorophenyl)acrylate (CAS 42175-03-1)
- (2-(4-Nitrophenoxy)phenyl)methanol (CAS 25562-37-2)
- 2-Chloro-7-(2,4-difluorophenyl)-N,5,5-trimethyl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-amine (CAS 2171305-33-0)
- 4-Cyclopropoxy-1-isopropyl-2-nitrobenzene (CAS 1243446-58-3)
- Nintedanib Impurity 139 (CAS CATO-C4X-1814139)
- 4-Methyl-2-phenylpyrazolidin-3-one (CAS 14776-41-1)
- Semaglutide impurity 103 (CAS 1446013-07-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com