Apixaban Impurity 4 (BMS-728626-01) CAS 1686149-74-5
| CAS No. | 1686149-74-5 |
| Molecular Formula | C26H27N5O4 |
| Molecular Weight | 473.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Apixaban Impurity 4 (BMS-728626-01) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Apixaban Impurity 4 (BMS-728626-01) (CAS 1686149-74-5) is a certified pharmaceutical impurity reference standard with the molecular formula C26H27N5O4 and a molecular weight of 473.52 g/mol.
Based on its molecular formula C26H27N5O4, Apixaban Impurity 4 (BMS-728626-01) contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 473.52 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C26H27N5O4 |
| Molecular Weight | 473.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Nitrogen Atoms | 5 |
Related Apixaban Standards
- Apixaban Impurity 137 (CAS CATO-C4X-1088137)
- Apixaban Impurity 155 (CAS 1928718-22-2)
- Apixaban Impurity 164 (CAS CATO-C4X-1088164)
- Apixaban Impurity 3 (BMS-778960-01) (CAS 2098457-92-0)
- Apixaban Impurity 8 (CAS 1074549-87-3)
- Apixaban Impurity 87 (CAS CATO-C4X-108887)
- Apixaban Impurity 88 (CAS CATO-C4X-108888)
- Apixaban Impurity 6 (CAS 1074365-84-6)
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