Apixaban Impurity 87 CAS CATO-C4X-108887
| CAS No. | CATO-C4X-108887 |
| Molecular Formula | C26H27N5O4 |
| Molecular Weight | 473.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Apixaban Impurity 87 (CAS CATO-C4X-108887, C26H27N5O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Apixaban Impurity 87 (C26H27N5O4) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Apixaban Impurity 87 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C26H27N5O4 |
| Molecular Weight | 473.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Apixaban Standards
- Apixaban Impurity 137 (CAS CATO-C4X-1088137)
- Apixaban Impurity 155 (CAS 1928718-22-2)
- Apixaban Impurity 164 (CAS CATO-C4X-1088164)
- Apixaban Impurity 3 (BMS-778960-01) (CAS 2098457-92-0)
- Apixaban Impurity 4 (BMS-728626-01) (CAS 1686149-74-5)
- Apixaban Impurity 8 (CAS 1074549-87-3)
- Apixaban Impurity 88 (CAS CATO-C4X-108888)
- Apixaban Impurity 6 (CAS 1074365-84-6)
Recommended Standards
- Folic Acid Impurity 56 (CAS CATO-C4X-139556)
- Vibegron Impurity 9 (CAS CATO-C4X-23769)
- Vazegepant Impurity 14 (CAS 928014-62-4)
- Vazegepant Impurity 3 (CAS CATO-C4X-32003)
- Tirofiban Impurity 80 (CAS 5264-17-5)
- Sorafenib EP Impurity C (CAS 320-51-4)
- Ruxolitinib Impurity 8 (CAS 2606144-45-8)
- 2-Bromo-1-nitro-3-(trifluoromethyl)benzene (CAS 24034-22-8)
- 1-(3-Fluoro-2-nitrophenyl)piperidin-4-ol (CAS 1286272-69-2)
- Pimecrolimus Impurity 11 (CAS CATO-C4X-173111)
- 5-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzene-1,3-dicarboxylic acid (CAS 55738-70-0)
- Lenalidomide Impurity 41 (CAS CATO-C4X-190341)
- 0847AD 1201633-60-4 C13H22ClNO {2-[3-(3-Methylbutoxy)phenyl]ethyl}amine hydrochloride (CAS 1201633-60-4)
- Steroidogenesis-Activator Polypeptide (rat) (H-8855.0500) (CAS 108563-23-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com