Isoprenaline Hydrochloride EP Impurity A CAS 16899-81-3
| CAS No. | 16899-81-3 |
| Molecular Formula | C11H15NO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Isoprenaline Hydrochloride EP Impurity A (CAS 16899-81-3), a pharmacopoeial impurity reference standard (molecular formula C11H15NO3HCl, MW 245.70 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C11H15NO3HCl, Isoprenaline Hydrochloride EP Impurity A contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 245.70 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C11H15NO3 HCl |
| Molecular Weight | 245.70 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Isoprenaline Standards
- Isoprenaline Impurity 23 HCl (CAS 13725-13-8(free base))
- Isoprenaline Impurity 3 (CAS 14309-63-8)
- Isoprenaline Sulphate Dihydrate (CAS 299-95-6)
- Isoprenaline Hydrochloride (CAS 51-30-9)
- Isoprenaline sulfate CRS (CAS 6078-56-4)
- Isoprenaline Impurity 22 HCl (CAS 721917-88-0(free base))
- Isoprenaline Impurity 1 (CAS CATO-C4X-27751)
- Isoprenaline Impurity 15 (CAS CATO-C4X-277515)
Recommended Standards
- Capecitabine Impurity 36 (CAS 1993-63-1)
- Tepotinib impurity 16 (CAS CATO-C4X-337416)
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- 5-[(3-chloro-4-methylphenyl)amino]-1,3,4-thiadiazole-2-thiol (CAS 873810-46-9)
- 5-Bromo-4-chloro-3-indolyl β-D-glucuronide sodium salt, 98% (CAS 129541-41-9)
- 6-Fluoro-1H-indene (CAS 52163-88-9)
- 3-(Pyrimidin-4-yloxy)phenol (CAS 1251224-95-9)
- [3,5 Diiodo-Tyr7] Peptide T (CAS 128551-40-6)
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