Rosuvastatin EP Impurity A (Calcium Salt) CAS 1714147-47-3
| CAS No. | 1714147-47-3 |
| Molecular Formula | 2*C25H33FN3O7S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 578.69 g/mol gives Rosuvastatin EP Impurity A (Calcium Salt) distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Rosuvastatin EP Impurity A (Calcium Salt) (CAS 1714147-47-3, C25H33FN3O7SCa) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Rosuvastatin EP Impurity A (Calcium Salt) (C25H33FN3O7SCa) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | 2*C25H33FN3O7S Ca |
| Molecular Weight | 578.69 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Rosuvastatin Standards
- Rosuvastatin Impurity 205 (CAS 1007871-85-3)
- Rosuvastatin EP Impurity L Calcium(Mixture of Diastereomers) (CAS 1024064-70-7)
- Rosuvastatin Impurity 267 (CAS 1031246-43-1)
- Rosuvastatin Impurity 19 (CAS 1035595-71-1)
- Rosuvastatin Impurity 27 (CAS 1044518-75-3)
- Rosuvastatin Impurity 192 (CAS 1092844-00-2)
- Rosuvastatin Impurity 123 (CAS 1112048-62-0)
- Rosuvastatin Impurity 37 (CAS 1197348-98-3)
Recommended Standards
- Montelukast Impurity 50 (CAS 1044705-96-5)
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- Ampicillin Impurity 56 (CAS CATO-C4X-144356)
- Carbon (Amorphous) (13C, 99 atom %) (CAS 14762-74-4)
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- (2S,6S)-2,6-Dimethylpiperidin-4-one (CAS 1932600-38-8)
- 2-(4-Methoxyphenyl)-5-phenyl-1,3,4-thiadiazole (CAS 1456-67-3)
- Dimethyl (3-(4-chlorophenoxy)-2-oxopropyl)phosphonate (CAS 40665-86-9)
- (4-(1-Aminocyclopropyl)phenyl)boronic acid hydrochloride (CAS 1256345-72-8)
- Des-Lys16-Tirzepatide (CAS CATO-CPTD788957)
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