Paclitaxel EP Impurity A CAS 173101-54-7
| CAS No. | 173101-54-7 |
| Molecular Formula | C45H53NO14 |
| Molecular Weight | 831.90 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Paclitaxel EP Impurity A (CAS 173101-54-7), a pharmacopoeial impurity reference standard (molecular formula C45H53NO14, MW 831.90 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Paclitaxel EP Impurity A is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 831.90 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Paclitaxel EP Impurity A meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C45H53NO14 |
| Molecular Weight | 831.90 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2006 |
| Nitrogen Atoms | 1 |
Related Paclitaxel Standards
- Paclitaxel Impurity 18 (CAS CATO-C4X-184218)
- Paclitaxel EP Impurity B (CAS 71610-00-9)
- Paclitaxel EP Impurity D (CAS 150547-36-7)
- Paclitaxel EP Impurity R (CAS 158948-96-0)
- Paclitaxel Impurity R (CAS 159001-25-9)
- Paclitaxel Impurity 38 (CAS 173101-55-8)
- Paclitaxel Impurity 58 (CAS CATO-C4X-184258)
- Paclitaxel Impurity 61 (CAS CATO-C4X-184261)
Recommended Standards
- Abz-Phe-Arg-Lys(Dnp)-Pro-OH (CAS 500799-61-1)
- N-[(11bR)-2,6-Di-9-anthracenyl-4-oxidodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl]-1,1,1-trifluoromethanesulfonamide (CAS 957790-95-3)
- 1,1,1-Trifluoro-N-[(11bS)-8,9,10,11,12,13,14,15-octahydro-4-oxido-2,6-di-9-phenanthrenyldinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl]methanesulfonamide (CAS 2757287-60-6)
- 1,1,1-Trifluoro-N-[(11bR)-4-oxido-2,6-di-9-phenanthrenyldinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl]methanesulfonamide (CAS 937028-51-8)
- Lornoxicam impurity 67 (CAS CATO-C4X-201667)
- Relebactam Impurity 1 (CAS 2382365-77-5)
- Salbutamol Impurity 63 (CAS CATO-C4X-117663)
- 2-(Benzyloxy)-5-nitropyridine (CAS 75926-54-4)
- 1-(Methylthio)-5,6,7,8-tetrahydro-5,8-methanoisoquinoline (CAS 145041-54-9)
- 4-Cyclopropoxy-3-methoxypyridine (CAS 1243322-86-2)
- 2-(4-Isopropylphenoxy)ethane-1-sulfonyl chloride (CAS 1018340-55-0)
- N-Cyclohexylacetamide (CAS 1124-53-4)
- 5-(Ethylsulfonyl)-4-(o-tolyl)pyrimidin-2-amine (CAS 1708445-14-0)
- Peptide 432 (CAS CATO-CPTD788432)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com