Paclitaxel EP Impurity B CAS 71610-00-9
| CAS No. | 71610-00-9 |
| Molecular Formula | C45H53NO14 |
| Molecular Weight | 831.90 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Paclitaxel EP Impurity B (CAS 71610-00-9) is a certified pharmaceutical impurity reference standard with the molecular formula C45H53NO14 and a molecular weight of 831.90 g/mol.
The molecular framework of Paclitaxel EP Impurity B (C45H53NO14) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C45H53NO14 |
| Molecular Weight | 831.90 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Nitrogen Atoms | 1 |
Related Paclitaxel Standards
- Paclitaxel EP Impurity A (CAS 173101-54-7)
- Paclitaxel Impurity 18 (CAS CATO-C4X-184218)
- Paclitaxel EP Impurity D (CAS 150547-36-7)
- Paclitaxel EP Impurity R (CAS 158948-96-0)
- Paclitaxel Impurity R (CAS 159001-25-9)
- Paclitaxel Impurity 38 (CAS 173101-55-8)
- Paclitaxel Impurity 58 (CAS CATO-C4X-184258)
- Paclitaxel Impurity 61 (CAS CATO-C4X-184261)
Recommended Standards
- Larotaxel (CAS 156294-36-9)
- Abz-Phe-Arg-Lys(Dnp)-Pro-OH (CAS 500799-61-1)
- (Z)-((Dimethylstannanediyl)bis(sulfanediyl))bis(ethane-2,1-diyl) dioleate (CAS 67859-63-6)
- N-[(11bR)-2,6-Di-9-anthracenyl-4-oxidodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl]-1,1,1-trifluoromethanesulfonamide (CAS 957790-95-3)
- Etoricoxib impurity 65 (CAS 856434-46-3)
- Saxagliptin Impurity 7 (CAS 1564266-54-1)
- Tepotinib impurity 28 (CAS CATO-C4X-337428)
- Harpagide (CAS 6926-08-5)
- Methyl 3-amino-5-(3-chlorophenyl)thiophene-2-carboxylate (CAS 304477-85-8)
- (R)-N,1-Dimethyl-5-oxopyrrolidine-2-carboxamide (CAS 182803-79-8)
- 4-(4-Chlorophenyl)-6-hydroxy-2-(pyridin-2-yl)pyrimidine-5-carbonitrile (CAS 1797296-66-2)
- 4,6-Dichloro-5-methyl-2-(propan-2-yl)pyrimidine (CAS 617716-43-5)
- Methyl 3,5-dichloro-2-fluorophenylacetate (CAS 1803777-40-3)
- Semaglutide impurity 38 (CAS CATO-C4X-222638)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com