Lumefantrine Impurity 3 CAS 1795129-61-1
| CAS No. | 1795129-61-1 |
| Molecular Formula | C44H24Cl6O2 |
| Molecular Weight | 797.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Lumefantrine Impurity 3 is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Lumefantrine Impurity 3 (CAS 1795129-61-1, C44H24Cl6O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system, Lumefantrine Impurity 3 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 797.38 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Lumefantrine Impurity 3 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C44H24Cl6O2 |
| Molecular Weight | 797.38 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 30.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Cl-containing |
Related Lumefantrine Standards
- Lumefantrine Impurity 4 (CAS 1795128-25-4)
- Lumefantrine D18 (CAS 1185240-53-2)
- Lumefantrine-d9 (Benflumetol-d9) (CAS 2477594-24-2)
- (9E)-Lumefantrine (CAS 1456736-33-6)
- LUMEFANTRINE (CAS 204133-10-8)
- Lumefantrine Impurity 1 (CAS 1331642-68-2)
- Lumefantrine Impurity 14 (CAS 2170653-95-7)
- Lumefantrine (CAS 82186-77-4)
Recommended Standards
- Ubidecarenone impurity 19 (CAS 5677-54-3)
- O,O′′-Bis[2-(methylthio)ethyl]-tert-butylcalix[4]arene (CAS 145237-25-8)
- Sitagliptin Impurity 40 (CAS CATO-C4X-1144140)
- ((((Propane-2,2-diylbis(4,1-phenylene))bis(oxy))bis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) ditridecanoate (CAS 105589-05-7)
- Levofloxacin Impurity 96 (CAS CATO-C4X-137196)
- Sitagliptin Impurity 71 (CAS CATO-C4X-114471)
- Brivaracetam Impurity 183 (CAS CATO-C4X-2007183)
- 4-Methyl-3-nitrothiophen-2-amine (CAS 80313-10-6)
- 3-fluoro-1,2-dihydroquinolin-2-one (CAS 124467-22-7)
- Morpholino(4-phenyl-1,2,3-thiadiazol-5-yl)methanone (CAS 477857-70-8)
- N-but-3-ynyl-2-(2,6-dioxo-3-piperidyl)-1-oxo-isoindoline-4-carboxamide (CAS 2761410-18-6)
- 2-(Oxiran-2-yl)ethane-1-sulfonyl chloride (CAS 1640118-61-1)
- N,N'-((1S,2S)-Cyclohexane-1,2-diyl)dimethanesulfonamide (CAS 220150-70-9)
- Insulin Degludec Impurity 15 (CAS CATO-C4X-215715)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com