Lamotrigine Impurity 22 CAS CATO-C4X-167222
| CAS No. | CATO-C4X-167222 |
| Molecular Formula | C14H6Cl4O3 |
| Molecular Weight | 364.01 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 364.01 g/mol gives Lamotrigine Impurity 22 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Lamotrigine Impurity 22 (CAS CATO-C4X-167222), a pharmacopoeial impurity reference standard (molecular formula C14H6Cl4O3, MW 364.01 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C14H6Cl4O3, Lamotrigine Impurity 22 contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 364.01 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H6Cl4O3 |
| Molecular Weight | 364.01 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Lamotrigine Standards
- Lamotrigine EP Impurity F (CAS 252186-79-1)
- Lamotrigine N-Acetate (CAS 77668-57-6)
- Lamotrigine-2N-glucuronide (CAS 135288-68-5)
- Lamotrigine 5 N Glucuronide (CAS 136565-77-0)
- Lamotrigine N2-Glucuronide (CAS 133310-19-7)
- Lamotrigine Impurity 11 (CAS CATO-C4X-167211)
- Lamotrigine Impurity 13 (CAS CATO-C4X-167213)
- Lamotrigine Impurity 14 (CAS CATO-C4X-167214)
Recommended Standards
- Ixazomib-13C2,15N (CAS CATO-C4X-126764)
- 1-Chloro-1,1-Difluoro-Pentan-2-Ol (CAS 6301-96-8)
- 3,4-Dichlorobenzoic anhydride (CAS 86866-14-0)
- 10,11-Dibromo-5H-dibenzo[a,d][7]annulen-5-one (CAS 137837-76-4)
- Cefotiam Impurity 21 (CAS CATO-C4X-120421)
- Fluticasone Impurity 51 (CAS CATO-C4X-165051)
- Sofosbuvir Impurity 78 (CAS CATO-C4X-105278)
- 2-((1-(3-Chlorophenyl)-1H-imidazol-2-yl)thio)-N-(2,5-dimethoxyphenyl)acetamide (CAS 851079-13-5)
- 3-(3-Chlorophenyl)picolinic acid (CAS 1225514-91-9)
- 1-(Benzo[d]thiazol-2-yl)azetidin-3-yl 2-(thiophen-2-yl)acetate (CAS 1396843-49-4)
- 5-Chloro-2-methyl-6-(trifluoromethyl)pyridin-3-amine (CAS 2869955-60-0)
- 5-Hydrazinyl-4-methyl-3-phenylisoxazole (CAS 25388-07-2)
- 2-[(2-Benzamido-3-methylbutanoyl)amino]acetic acid (CAS 138738-22-4)
- Semaglutide impurity 289 (CAS CATO-C4X-2226289)
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