1-(4-Chloro-3-(trifluoromethyl)phenyl)-5-oxopyrrolidine-3-carboxylic acid CAS 1799-70-8
| CAS No. | 1799-70-8 |
| Molecular Formula | C12H9ClF3NO3 |
| Molecular Weight | 307.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 307.65 g/mol gives 1-(4-Chloro-3-(trifluoromethyl)phenyl)-5-oxopyrrolidine-3-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 1-(4-Chloro-3-(trifluoromethyl)phenyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 1799-70-8), a certified reference material (molecular formula C12H9ClF3NO3, MW 307.65 g/mol) for analytical method development and quality control.
Structurally, 1-(4-Chloro-3-(trifluoromethyl)phenyl)-5-oxopyrrolidine-3-carboxylic acid (C12H9ClF3NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 307.65 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(4-Chloro-3-(trifluoromethyl)phenyl)-5-oxopyrrolidine-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H9ClF3NO3 |
| Molecular Weight | 307.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 8-Chloro-1,3-dinitro-10H-phenoxazine (CAS 105261-75-4)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-5-ethoxy-2,4-dihydro-3H-pyrazol-3-one (CAS 338420-89-6)
- 2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one (CAS 97986-18-0)
- 3-{[(4-chloro-6-methylpyrimidin-2-yl)amino]methylene}-1,1,1-trifluoropentane-2,4-dione (CAS 649665-78-1)
- 4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)(methyl)amino)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 860650-63-1)
- Ethyl 3-chloro-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-6-carboxylate (CAS 685108-15-0)
- Methyl 4-chloro-6-fluoro-2-(trifluoromethyl)quinoline-3-carboxylate (CAS 1384264-64-5)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-5-fluoro-4-hydrazinylpyrimidine (CAS 1823183-39-6)
Recommended Standards
- Urapidil impurity 100 (CAS CATO-C4X-1924100)
- 5-Bromo-3-chloro-N-(2,2-dimethylthietan-3-yl)pyridin-2-amine (CAS 1870100-35-8)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-5-fluoro-6-methylpyrimidin-4(3H)-one (CAS 1823183-47-6)
- 4-Hydroxy-5-methoxy-2-(trifluoromethoxy)pyridine-3-sulfonyl chloride (CAS 1804312-70-6)
- 3-Aminobicyclo[2.1.0]Pentane-1-carboxylic acid (CAS 2384421-71-8)
- 7-Iodo-5-(o-tolyl)quinolin-8-ol (CAS 648896-59-7)
- 3-(4-Chlorophenyl)-3-methylbutan-1-ol (CAS 1509751-84-1)
- 1-(4-(tert-Butyl)phenyl)-N-methylmethanamine (CAS 65542-26-9)
- 6-Chloro-2-cyclohexylpyrimidin-4(1H)-one (CAS 80683-13-2)
- 4-{2-[2-Nitro-4-(trifluoromethyl)phenoxy]-ethyl}piperidine hydrochloride (CAS 1220032-56-3)
- Ethyl 1-cyclohexyl-1h-pyrazole-4-carboxylate (CAS 1497762-78-3)
- 2,2'-(2-Fluoro-1,3-phenylene)diacetonitrile (CAS 175136-84-2)
- 3-(2-(Allylthio)ethyl)thietane 1,1-dioxide (CAS 1878955-64-6)
- Hexapeptide-11 (CAS 161258-30-6)
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