2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-5-ethoxy-2,4-dihydro-3H-pyrazol-3-one CAS 338420-89-6
| CAS No. | 338420-89-6 |
| Molecular Formula | C11H9ClF3N3O2 |
| Molecular Weight | 307.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-5-ethoxy-2,4-dihydro-3H-pyrazol-3-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-5-ethoxy-2,4-dihydro-3H-pyrazol-3-one (CAS 338420-89-6), a certified reference material (molecular formula C11H9ClF3N3O2, MW 307.66 g/mol) for analytical method development and quality control.
Structurally, 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-5-ethoxy-2,4-dihydro-3H-pyrazol-3-one (C11H9ClF3N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 307.66 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H9ClF3N3O2 |
| Molecular Weight | 307.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one (CAS 97986-18-0)
- 3-{[(4-chloro-6-methylpyrimidin-2-yl)amino]methylene}-1,1,1-trifluoropentane-2,4-dione (CAS 649665-78-1)
- 4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)(methyl)amino)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 860650-63-1)
- Ethyl 3-chloro-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-6-carboxylate (CAS 685108-15-0)
- 8-Chloro-1,3-dinitro-10H-phenoxazine (CAS 105261-75-4)
- 1-(4-Chloro-3-(trifluoromethyl)phenyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 1799-70-8)
- 7-Chloro-6-fluoro-1-(4-fluorophenyl)-3-hydroxyquinolin-4(1H)-one (CAS 188967-75-1)
- 4-(2-chloro-4-fluorosulphonylanilino)-4-oxobut-2-enoic acid (CAS 680213-38-1)
Recommended Standards
- Urapidil impurity 100 (CAS CATO-C4X-1924100)
- 5-Bromo-3-chloro-N-(2,2-dimethylthietan-3-yl)pyridin-2-amine (CAS 1870100-35-8)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-5-fluoro-6-methylpyrimidin-4(3H)-one (CAS 1823183-47-6)
- Norflurazon-13C,d3 (CAS 1346603-47-1)
- 1,17-Bisbiotinylamino-3,6,9,12,15-pentaoxaheptadecane (CAS 440680-87-5)
- 3-Acetoxy-3-iodobenzophenone (CAS 890099-65-7)
- 1,3,3a,4,7,7a-Hexahydroisobenzofuran (CAS 4743-55-9)
- Hydroxy Darunavir (CAS 1130635-75-4)
- Methyl 4-[4-(benzyloxy)phenyl]-2-chlorobenzoate (CAS 1820687-92-0)
- (2-Aminopropyl)(ethyl)amine (CAS 68713-14-4)
- 2-(sec-Butyl)-6-(furan-2-yl)pyridazin-3(2H)-one (CAS 1209103-36-5)
- 2,6-dibromo-4-(2H-1,2,3,4-tetrazol-5-yl)phenol (CAS 874815-07-3)
- 2-(Methyl(piperidin-4-yl)amino)ethan-1-ol dihydrochloride (CAS 864655-27-6)
- ([13C6]Leu14)-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt (CAS 1802078-39-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com