2,4-Dichlorobenzyl Alcohol EP Impurity C CAS 1805-32-9
| CAS No. | 1805-32-9 |
| Molecular Formula | C7H6Cl2O |
| Molecular Weight | 177.03 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,4-Dichlorobenzyl Alcohol EP Impurity C.
CATO supplies 2,4-Dichlorobenzyl Alcohol EP Impurity C (CAS 1805-32-9), a pharmacopoeial impurity reference standard (molecular formula C7H6Cl2O, MW 177.03 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 2,4-Dichlorobenzyl Alcohol EP Impurity C is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 177.03 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H6Cl2O |
| Molecular Weight | 177.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
Related Dichlorobenzyl Standards
- 3,5-Dichlorobenzyl alcohol (CAS 60211-57-6)
- 2,3-Dichlorobenzyl alcohol (CAS 38594-42-2)
- 2,4-Dichlorobenzyl Alcohol EP Impurity A (CAS 34145-05-6)
- 2,6-Dichlorobenzyl Alcohol (CAS 15258-73-8)
- 2,4-Dichlorobenzyl Alcohol (CAS 1777-82-8)
- 2,4-Dichlorobenzyl Alcohol EP Impurity F (CAS 874-42-0)
- 2,5-Dichlorobenzyl cyanide (CAS 3218-50-6)
- (2,3-Dichlorobenzyl)hydrazine (CAS 51421-26-2)
Recommended Standards
- Prostaglandin Impurity 15 (CAS 5307-99-3)
- Voriconazole Impurity 70 (CAS 115617-41-9)
- Prostaglandin Impurity 17 (CAS 63319-59-5)
- 1,4-Dichloro-2-Methoxybenzene (CAS 1984-58-3)
- Cefuroxime Axetil Impurity 13 (CAS CATO-C4X-143613)
- Paroxetine Impurity 51 (CAS CATO-C4X-103551)
- Arbidol Impurity 17 (CAS CATO-C4X-112917)
- 2-Bromo-5-(3,3-difluoropiperidin-1-yl)benzonitrile 1707572-72-2 (CAS 1707572-72-2)
- 2-Aminoethyl methanethiosulfonate hydrochloride (CAS 37597-96-9)
- 1-{[2-(4-methoxyphenoxy)-1,3-thiazol-5-yl]methyl}-4-phenylpiperazine (CAS 439097-05-9)
- 7-Methyl-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepine (CAS 51585-35-4)
- 5-(tert-Butylthio)-N-isopropyl-3-methylpyridin-2-amine (CAS 1355174-03-6)
- 4-Ethoxy-3,3-difluoropiperidine (CAS 2168646-29-3)
- Tyr-Proinsulin C-Peptide (55-89) (human) (CAS 139532-11-9)
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