2,4-Dichlorobenzyl Alcohol EP Impurity A CAS 34145-05-6
| CAS No. | 34145-05-6 |
| Molecular Formula | C7H6Cl2O |
| Molecular Weight | 177.03 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2,4-Dichlorobenzyl Alcohol EP Impurity A (CAS 34145-05-6), a pharmacopoeial impurity reference standard (molecular formula C7H6Cl2O, MW 177.03 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C7H6Cl2O, 2,4-Dichlorobenzyl Alcohol EP Impurity A contains a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 177.03 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), 2,4-Dichlorobenzyl Alcohol EP Impurity A meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H6Cl2O |
| Molecular Weight | 177.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | Cl-containing |
Related Dichlorobenzyl Standards
- 3,5-Dichlorobenzyl alcohol (CAS 60211-57-6)
- 2,3-Dichlorobenzyl alcohol (CAS 38594-42-2)
- 2,4-Dichlorobenzyl Alcohol EP Impurity C (CAS 1805-32-9)
- 2,6-Dichlorobenzyl Alcohol (CAS 15258-73-8)
- 2,4-Dichlorobenzyl Alcohol (CAS 1777-82-8)
- 2,4-Dichlorobenzyl Alcohol EP Impurity F (CAS 874-42-0)
- 2,5-Dichlorobenzyl cyanide (CAS 3218-50-6)
- (2,3-Dichlorobenzyl)hydrazine (CAS 51421-26-2)
Recommended Standards
- Voriconazole Impurity 70 (CAS 115617-41-9)
- 1,4-Dichloro-2-Methoxybenzene (CAS 1984-58-3)
- Prostaglandin Impurity 15 (CAS 5307-99-3)
- Prostaglandin Impurity 17 (CAS 63319-59-5)
- Oseltamivir Impurity 237 DiHCI (CAS 212504-90-0（free base）)
- Tenofovir alafenamide impurity 73 (CAS CATO-C4X-179773)
- Firocoxib Impurity 6 (CAS CATO-C4X-32116)
- 4-Methyl-5-(naphthalen-2-ylsulfanyl)-1,2,3-thiadiazole (CAS 338408-56-3)
- 2,2,2-Trifluoro-1-(5-fluoro-2-(hexyloxy)phenyl)ethan-1-one (CAS 1443350-59-1)
- 1-methyl-1H-imidazole-2-sulfonyl fluoride (CAS 934236-37-0)
- 4-Chloro-5,6-dimethyl-2-(trifluoromethyl)pyrimidine (CAS 175277-32-4)
- Edaravone impurity 37 (CAS CATO-C4X-106237)
- 4-Amino-5-carboxy-2-ethylmercaptopyrimidine (CAS 89853-87-2)
- Galanin-Like Peptide (human) trifluoroacetate salt (CAS 245114-99-2)
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