2-Chloro-4-fluoropyridin-3-amine CAS 1805269-43-5

Purity 97%+In StockPharmaceutical Standards
CAS No.1805269-43-5
Molecular FormulaC5H4ClFN2
Molecular Weight146.55 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Chloro-4-fluoropyridin-3-amine CAS 1805269-43-5 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

2-Chloro-4-fluoropyridin-3-amine (CAS 1805269-43-5), molecular formula C5H4ClFN2 and molecular weight 146.55 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrile group, fluorine/chlorine substitution, 2-Chloro-4-fluoropyridin-3-amine is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 146.55 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC5H4ClFN2
Molecular Weight146.55 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1995
Halogen ContentF/Cl-containing
Nitrogen Atoms2

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