Apalutamide Impurity 47 CAS 1805396-62-6
| CAS No. | 1805396-62-6 |
| Molecular Formula | C7H4F3N3 |
| Molecular Weight | 187.12 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Apalutamide Impurity 47 (CAS 1805396-62-6, C7H4F3N3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Apalutamide Impurity 47 (C7H4F3N3) is characterized by a nitrile group, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Apalutamide Impurity 47 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H4F3N3 |
| Molecular Weight | 187.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Apalutamide Standards
- Apalutamide Impurity 14 (CAS 573762-62-6)
- Apalutamide Impurity 48 (CAS 1805601-57-3)
- Apalutamide Impurity 81 (CAS CATO-C4X-274981)
- Apalutamide Impurity 43 (CAS 1513700-34-9)
- Apalutamide Impurity 49 (CAS CATO-C4X-274949)
- Apalutamide Impurity 21 (CAS CATO-C4X-274921)
- Apalutamide Impurity 37 (CAS CATO-C4X-274937)
- Apalutamide Impurity 63 (CAS 199330-60-4)
Recommended Standards
- Sorafenib Impurity 20 (CAS 329-01-1)
- 3-(Difluoromethoxy)-4-fluorobenzonitrile 916210-09-8 (CAS 916210-09-8)
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- Selenopheno[3,2-b]thiophene (CAS 20503-37-1)
- Pemetrexed Impurity 31 ·1.5H2O (CAS CATO-C4X-172631)
- Silodosin Impurity 18 (CAS 160969-02-8)
- Norepinephrine impurity 140 (CAS CATO-C4X-1514140)
- 3-Oxo-2-(triphenylphosphoranylidene)butanoic acid (CAS 184000-45-1)
- 2-[2-(3-Isopropylphenoxy)ethyl]piperidinehydrochloride (CAS 1219982-57-6)
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- 5-(4-Fluoro-phenyl)-N-hydroxy-2-methyl-furan-3-carboxamidine; hydrochloride (CAS 1993797-73-1)
- PKM2 inhibitor (Compound 3k) (CAS 94164-88-2)
- 1-Furan-2-yl-1,2,3,4-tetrahydro-isoquinoline (CAS 135675-29-5)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com