Olaparib Impurity 102 CAS 1806327-68-3
| CAS No. | 1806327-68-3 |
| Molecular Formula | C7H3Br2FO |
| Molecular Weight | 281.90 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Olaparib Impurity 102 (CAS 1806327-68-3, C7H3Br2FO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Olaparib Impurity 102 (C7H3Br2FO) contains a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H3Br2FO |
| Molecular Weight | 281.90 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Br-containing |
Related Olaparib Standards
- Olaparib Impurity 105 (CAS 477535-39-0)
- Olaparib Impurity 93 (CAS 1379332-00-9)
- Olaparib Impurity 58 (CAS CATO-C4X-113558)
- Olaparib Impurity 59 (CAS CATO-C4X-113559)
- Olaparib Impurity 89 (Mixture E&Z) (CAS CATO-C4X-113589)
- Olaparib Impurity 14 (CAS 420846-72-6)
- Olaparib Impurity 37 (CAS 1423030-11-8)
- Olaparib Impurity 76 (CAS CATO-C4X-113576)
Recommended Standards
- 3,6-Dibromo-2-fluorobenzaldehyde (CAS 870703-68-7)
- 3,5-Dibromo-2-fluorobenzaldehyde (CAS 477535-40-3)
- 2,6-Dibromo-4-fluorobenzaldehyde (CAS 938467-02-8)
- (4-(2-Borono-3-(methoxymethoxy)phenyl)butyl)boronic acid (CAS 502635-30-5)
- Amidotrizoate EP Impurity A (CAS 1713-07-1)
- Nimodipine impurity 28 (CAS 14205-46-0)
- Ebastine Impurity 13 (CAS 97928-34-2)
- Salmeterol EP Impurity B (CAS 94749-02-7)
- Methyl 5-acetyl-3-ethylisoxazole-4-carboxylate (CAS 175277-79-9)
- 3-Ethyl-2-fluoro-4-iodo-5-methylpyridine (CAS 1449786-43-9)
- 2-(Chloromethyl)-6-(difluoromethyl)-3-iodopyridine-5-acetic acid (CAS 1806957-87-8)
- 4-Methoxyphenyl acetate (CAS 1200-06-2)
- (1R,3R)-N-Boc-3-aminocyclohexanecarboxylic Acid (CAS 1430938-32-1)
- Liraglutide (13-21) TFA Salt (CAS CATO-C4X-19928)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com