Olaparib Impurity 76 CAS CATO-C4X-113576
| CAS No. | CATO-C4X-113576 |
| Molecular Formula | C16H9FO4 |
| Molecular Weight | 284.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Olaparib Impurity 76 (CAS CATO-C4X-113576, C16H9FO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C16H9FO4, Olaparib Impurity 76 contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 284.24 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H9FO4 |
| Molecular Weight | 284.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Olaparib Standards
- Olaparib Impurity 37 (CAS 1423030-11-8)
- Olaparib Impurity 58 (CAS CATO-C4X-113558)
- Olaparib Impurity 59 (CAS CATO-C4X-113559)
- Olaparib Impurity 89 (Mixture E&Z) (CAS CATO-C4X-113589)
- Olaparib Impurity 102 (CAS 1806327-68-3)
- Olaparib Impurity 105 (CAS 477535-39-0)
- Olaparib Impurity 93 (CAS 1379332-00-9)
- Olaparib Impurity 14 (CAS 420846-72-6)
Recommended Standards
- Ataluren Impurity 6 (CAS 775304-58-0)
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- 1-(5-Fluoro-2,4-Dinitrophenyl)-4-Methylpiperazine (CAS 928830-73-3)
- Ataluren Impurity N (CAS 775304-56-8)
- Rosuvastatin Impurity 160 (CAS CATO-C4X-1169160)
- Atracurium Impurity 89 (CAS CATO-C4X-185089)
- Betaxolol Impurity 18 (CAS CATO-C4X-155918)
- methyl 4,5-dihydroxypyrrolo[2,1-f][1,2,4]triazine-6-carboxylate (CAS 1784944-87-1)
- 6-methyl-5H,6H,7H,8H-imidazo[1,2-a]pyridine-2-carboxylic acid hydrochloride (CAS 2060006-29-1)
- 2-(2-((2,6-Dichloro-4-methoxyphenyl)amino)phenyl)-N,N-dimethylacetamide (CAS 698357-36-7)
- 2-(tert-Butylsulfonyl)-2-[2-(3-methoxyphenyl)hydrazono]acetonitrile (CAS 241127-20-8)
- 4-(Hydroxymethyl)-2,6-piperidinedione (CAS 171522-80-8)
- N-Benzyl-o-t-butyl-l-serine methyl ester, HCl (CAS 670278-82-7)
- Cholecystokinin, CCK Tetrapeptide (30-33) (CAS 35144-91-3)
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